Evidence map›Paper›PMID 33036201›Full record

Trial reportNutrients2020

A Partially Hydrolyzed Whey Infant Formula Supports Appropriate Growth: A Randomized Controlled Non-Inferiority Trial.

Eva Karaglani, Inge Thijs-Verhoeven, Marjan Gros, Christina Chairistanidou, Giorgos Zervas, Christina Filoilia, Tarek-Michail Kampani, Vasileios Miligkos, Maria Matiatou, Stavroula Valaveri and 4 more

Abstract readRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematic Review to Reassess the Formula for Early Life Growth.Advances in nutrition (Bethesda, Md.) · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Eva KaraglaniDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Ave, 17671 Athens, Greece.ORCID 0000-0001-5395-7023
Inge Thijs-VerhoevenFrieslandCampina, Stationsplein 1, 3818 LE Amersfoort, The Netherlands.
Marjan GrosFrieslandCampina, Stationsplein 1, 3818 LE Amersfoort, The Netherlands.
Christina ChairistanidouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Ave, 17671 Athens, Greece.
Giorgos ZervasMitera hospital, 6 Erythrou Stavrou Str., 151 23 Athens, Greece.
Christina FiloiliaDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Ave, 17671 Athens, Greece.
Tarek-Michail KampaniDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Ave, 17671 Athens, Greece.
Vasileios MiligkosMitera hospital, 6 Erythrou Stavrou Str., 151 23 Athens, Greece.
Maria MatiatouMitera hospital, 6 Erythrou Stavrou Str., 151 23 Athens, Greece.
Stavroula ValaveriMitera hospital, 6 Erythrou Stavrou Str., 151 23 Athens, Greece.
Alexandros SakellariouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Ave, 17671 Athens, Greece.
Georgios BabilisMitera hospital, 6 Erythrou Stavrou Str., 151 23 Athens, Greece.
Rolf BosFrieslandCampina, Stationsplein 1, 3818 LE Amersfoort, The Netherlands.
Yannis ManiosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, 70 El. Venizelou Ave, 17671 Athens, Greece.ORCID 0000-0001-6486-114X

Funding

FrieslandCampina Nederland B.V. A1818AQ00
6 · The paper itself

Abstract

The aim of the current study was to investigate the effects of a partially hydrolyzed whey infant formula (PHF) on growth in healthy term infants as compared to a standard infant formula with intact protein (IPF). In a double-blind, non-inferiority, randomized controlled trial, a total of 163 healthy formula-fed infants, 55-80 days old, were recruited and randomly allocated to either the PHF (test) or the IPF (control) group. They were followed up for three months during which they were evaluated monthly on growth and development. In total, 21 infants discontinued the study, while 142 infants completed the study (test

Indexed as

Infant FormulaAge FactorsBody Mass IndexBody SizeChild DevelopmentDouble-Blind MethodEatingFemaleHealthy VolunteersHumansHydrolysisInfantInfant Nutritional Physiological PhenomenaMaleTime FactorsWeight Gainanthropometrygrowthinfant formulapartially hydrolyzed formulaprotein hydrolysate

Identifiers

PMID33036201
PMCPMC7650565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.