Evidence map›Paper›PMID 33036184›Full record

ReviewNutrients2020

The Role of Human Milk Oligosaccharides and Probiotics on the Neonatal Microbiome and Risk of Necrotizing Enterocolitis: A Narrative Review.

Lila S Nolan, Jamie M Rimer, Misty Good

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06035835 (Probiotics and Breastmilk Are Associated With a Decreased Risk of Atopic Dermatitis in Very Low Birth Weight Premature Infants), which is not on this map. Cited by 61 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 4 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06035835 completednot on this map

Probiotics and Breastmilk Are Associated With a Decreased Risk of Atopic Dermatitis in Very Low Birth Weight Premature Infants

TypeobservationalSponsorJosé Uberos FernándezRan2009 to 2022Enrolled437ConditionsAtopic DermatitisArmsLacticaseibacillus rhamnosus, Lactobacillus acidophilus + Bifidobacterium bifidum
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 110 citations in OpenAlex.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lila S NolanDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-4185-2686
Jamie M RimerDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Misty GoodDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-0264-5721
Washington University in St. Louis · US

Funding

Training of the Pediatric Physician-ScientistT32HD043010 · NICHD · WASHINGTON UNIVERSITY · PI MARK E. LOWE · 2002 to 2026
$6.4M
Neonatal gut-on-a-chip platform for high content drug testing and precision medicineR01HD105301 · NICHD · WASHINGTON UNIVERSITY · PI GOOD, MISTY L, MAGNESS, SCOTT T · 2021 to 2024
$2.4M
Modulation of the Intestinal Immune Response in Necrotizing EnterocolitisR01DK118568 · NIDDK · WASHINGTON UNIVERSITY · PI GOOD, MISTY L · 2018 to 2022
$1.8M
Children's Discovery Institute MI-FR-2017-596Foundation for the National Institutes of Health 5T32HD043010Foundation for the National Institutes of Health R01DK118568NICHD NIH HHS R01 HD105301NICHD NIH HHS T32 HD043010NIDDK NIH HHS R01 DK118568St. Louis Children's Hospital Foundation DR-2019-727
6 · The paper itself

Abstract

Preterm infants are a vulnerable population at risk of intestinal dysbiosis. The newborn microbiome is dominated by

Indexed as

Gastrointestinal MicrobiomeInfant, PrematureMilk, HumanDysbiosisEatingEnterocolitis, NecrotizingFemaleHomeostasisHumansInfant, NewbornInfant Nutritional Physiological PhenomenaIntestinesMaleOligosaccharidesProbioticsRiskOligosaccharidesbreast milkhuman milk oligosaccharidemicrobiomenecrotizing enterocolitisnewbornprematurityprobiotic

Identifiers

PMID33036184
PMCPMC7600747
OpenAlexW3092321065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.