ReviewAnimals : an open access journal from MDPI2020
Targeting the Hindgut to Improve Health and Performance in Cattle.
Review in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 59 citations in OpenAlex.
- Effects of rumen-protected glucose supplementation strategies on growth performance, colonic fermentation, and meat quality in Simmental beef cattle.Animal bioscience · 2026Article
- Strategies for Reducing Antimicrobial Use in Cattle Through Gut Microbiome Modulation: A Systematic Review of Alternatives to Antibiotics.Animals : an open access journal from MDPI · 2026Review
- Assessing gut barrier integrity in ruminants: structural, functional, and immunological approaches.Animal frontiers : the review magazine of animal agriculture · 2026Article
- Implications of leaky gut in cattle.Animal frontiers : the review magazine of animal agriculture · 2026Article
- Revisiting starch degradability in dairy ruminants: from feed processing to gut microbiota and metabolic regulation.Journal of animal science and biotechnology · 2026Review
- Effects of dietary starch concentration and feeding management regimen on bacterial pathogens in liver abscesses and ruminal and colonic epithelial tissues in feedlot steers.Journal of animal science · 2026Article
- Further delineation of the etiology of liver abscesses in cattle and indication of hindgut as a potential source of pathogens.Microbiology spectrum · 2025Article
- Effects of aAnimals : an open access journal from MDPI · 2025Article
- Welfare of beef cattle.EFSA journal. European Food Safety Authority · 2025Article
- The gastrointestinal tract microbiome of Holstein × Angus cross cattle is negatively impacted by the pre-harvest process.Applied and environmental microbiology · 2025Article
- Interactions between time on diet, antibiotic treatment, and liver abscess development on the fecal microbiome of beef cattle.Animal microbiome · 2025Article
- Fusobacterium varium in cattle: prevalence and concentrations in healthy livers, liver abscesses, and ruminal and colonic epithelial tissues.Journal of animal science · 2025Article
- The effects of induced hindgut acidosis in sheep on rumen fermentation and gut permeability.Journal of animal science · 2025Article
- Persistence of subacute ruminal acidosis across first and second lactations in dairy cows based on reticular pH metrics and microbiota, and systemic health responses.Journal of animal science · 2025Article
- Longitudinal assessment of the prevalence ofFrontiers in microbiology · 2025Article
- The effect of heat stress on the hindgut microbiota and metabolites of Simmental heifers.Frontiers in microbiology · 2025Article
- Effect of Milk-Feeding Frequency and Calcium Gluconate Supplementation on Growth, Health, and Reproductive and Metabolic Features of Holstein Heifers at a Rearing Farm.Animals : an open access journal from MDPI · 2024Article
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- A novel method for isolation and flow cytometry analysis of intraepithelial lymphocytes from colon biopsies.JDS communications · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An adequate gastrointestinal barrier function is essential to preserve animal health and well-being. Suboptimal gut health results in the translocation of contents from the gastrointestinal lumen across the epithelium, inducing local and systemic inflammatory responses. Inflammation is characterized by high energetic and nutrient requirements, which diverts resources away from production. Further, barrier function defects and inflammation have been both associated with several metabolic diseases in dairy cattle and liver abscesses in feedlots. The gastrointestinal tract is sensitive to several factors intrinsic to the productive cycles of dairy and beef cattle. Among them, high grain diets, commonly fed to support lactation and growth, are potentially detrimental for rumen health due to their increased fermentability, representing the main risk factor for the development of acidosis. Furthermore, the increase in dietary starch associated with such rations frequently results in an increase in the bypass fraction reaching distal sections of the intestine. The effects of high grain diets in the hindgut are comparable to those in the rumen and, thus, hindgut acidosis likely plays a role in grain overload syndrome. However, the relative contribution of the hindgut to this syndrome remains unknown. Nutritional strategies designed to support hindgut health might represent an opportunity to sustain health and performance in bovines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.