Evidence map›Paper›PMID 33036134›Full record

ReviewCancers2020

Testis Sparing Surgery in Pediatric Testicular Tumors.

Cezanne D Kooij, Caroline C C Hulsker, Mariëtte E G Kranendonk, József Zsiros, Annemieke S Littooij, Leendert H J Looijenga, Aart J Klijn, Annelies M C Mavinkurve-Groothuis

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Testicular cancer in adolescents: clinicopathological and immunohistochemical aspects.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cezanne D KooijPrincess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.ORCID 0000-0001-5985-0075
Caroline C C HulskerPrincess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.
Mariëtte E G KranendonkPrincess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.
József ZsirosPrincess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.
Annemieke S LittooijPrincess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.
Leendert H J LooijengaPrincess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.ORCID 0000-0002-8146-1911
Aart J KlijnDepartment of Pediatric Urology, University Medical Center Utrecht, 3584 Utrecht, The Netherlands.ORCID 0000-0002-3460-2961
Annelies M C Mavinkurve-GroothuisPrincess Máxima Center for Pediatric Oncology, 3584 Utrecht, The Netherlands.ORCID 0000-0002-6984-3626
Princess Máxima Center · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this review is to evaluate the outcomes of testis sparing surgery (TSS) and to investigate under which circumstances TSS can be considered a safe treatment option in pediatric patients with testicular tumors.

methodsA database search was performed in Cochrane, Pubmed, and Embase for studies that focused on TSS as treatment for testicular tumors in the pediatric population, excluding reviews and single case reports.

resultsTwenty studies, describing the surgical treatment of 777 patients with testicular tumors, were included in the analysis. The majority of pediatric patients with benign germ cell tumors (GCTs) (mean age: 3.7 years) and sex cord-stromal tumors (SCSTs) (mean age: 6.6 years) were treated with TSS, 61.9% and 61.2%, respectively. No cases of testicular atrophy occurred. Four of the benign GCTs, i.e., three teratomas and one epidermoid cyst, recurred. No cases of recurrence were reported in patients with SCSTs. Of the 243 malignant GCTs (mean age: 4.2 years), only one patient had TSS (0.4%).

conclusionTSS is a safe treatment option for prepubertal patients less than 12 years of age with benign GCTs and low grade SCSTs.

Indexed as

algorithmgerm cell tumorpediatricrecurrencetesticular atrophytesticular tumorsTestis sparing surgery

Identifiers

PMID33036134
PMCPMC7600997
OpenAlexW3091894309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.