ArticleNeuroImage. Clinical2020
Neonatal white matter tract microstructure and 2-year language outcomes after preterm birth.
Article in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Multimodal predictors of spoken vocabulary development in autism: the role of early childhood brain and behavior.Translational psychiatry · 2026Article
- White matter structure-function coupling in neonatal brain and its association with Autism-related traits in early childhood.Translational psychiatry · 2026Article
- The Relation of the Home Literacy Environment to White Matter Pathways Associated with Language in Children 5-8 Years Old.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Prenatal Adversity and Neonatal White Matter Microstructure Independently Relate to Language Outcomes at Age 2 Years.The Journal of pediatrics · 2025Article
- Whole-brain white matter variation across childhood environments.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Methodological considerations on diffusion MRI tractography in infants aged 0-2 years: a scoping review.Pediatric research · 2025Article
- Neonatal inflammation and near-term white matter microstructure in infants born very preterm.Neuroimage. Reports · 2024Article
- Interactive roles of preterm-birth and socioeconomic status in cortical thickness of language-related brain structures: Findings from the Adolescent Brain Cognitive Development (ABCD) study.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Early language processing efficiency and pre-literacy outcomes in children born full term and preterm.Journal of experimental child psychology · 2024Article
- Corpus Callosum Abnormalities at Term-Equivalent Age Are Associated with Language Development at 2 Years' Corrected Age in Infants Born Very Preterm.Journal of pediatrics. Clinical practice · 2024Article
- Corpus callosum abnormalities at term-equivalent age are associated with language development at two years corrected age in infants born very preterm.medRxiv : the preprint server for health sciences · 2023Article
- Associations between early efficiency in language processing and language and cognitive outcomes in children born full term and preterm: similarities and differences.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2023Article
- Neuroimaging of brain connectivity related to reading outcomes in children born preterm: A critical narrative review.Frontiers in pediatrics · 2023Review
- Association between attention-deficit/hyperactivity disorder symptom severity and white matter integrity moderated by in-scanner head motion.Translational psychiatry · 2022Article
- White matter myelination during early infancy is linked to spatial gradients and myelin content at birth.Nature communications · 2022Article
- Left and Right Arcuate Fasciculi Are Uniquely Related to Word Reading Skills in Chinese-English Bilingual Children.Neurobiology of language (Cambridge, Mass.) · 2022Article
- Microstructural Measures of the Inferior Longitudinal Fasciculus Predict Later Cognitive and Language Development in Infants Born With Extremely Low Birth Weight.Journal of child neurology · 2021Article
- Multi-Channel 4D Parametrized Atlas of Macro- and Microstructural Neonatal Brain Development.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
aimTo determine whether variability in diffusion MRI (dMRI) white matter tract metrics, obtained in a cohort of preterm infants prior to neonatal hospital discharge, would be associated with language outcomes at age 2 years, after consideration of age at scan and number of major neonatal complications.
method30 children, gestational age 28.9 (2.4) weeks, underwent dMRI at mean post menstrual age 36.4 (1.4) weeks and language assessment with the Bayley Scales of Infant Development-III at mean age 22.2 (1.7) months chronological age. Mean fractional anisotropy (FA) and mean diffusivity (MD) were calculated for 5 white matter tracts. Hierarchical linear regression assessed associations between tract FA, moderating variables, and language outcomes.
resultsFA of the left inferior longitudinal fasciculus accounted for 17% (p = 0.03) of the variance in composite language and FA of the posterior corpus callosum accounted for 19% (p = 0.02) of the variance in composite language, beyond that accounted for by post-menstrual age at scan and neonatal medical complications. The number of neonatal medical complications moderated the relationship between language and posterior corpus callosum FA but did not moderate the association in the other tract.
conclusionLanguage at age 2 is associated with white matter metrics in early infancy in preterm children. The different pattern of associations by fiber group may relate to the stage of brain maturation and/or the nature and timing of medical complications related to preterm birth. Future studies should replicate these findings with a larger sample size to assure reliability of the findings.
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