Evidence map›Paper›PMID 33035830›Full record

ReviewBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2020

Natural carbon-based quantum dots and their applications in drug delivery: A review.

Akhila Nair, Jozef T Haponiuk, Sabu Thomas, Sreeraj Gopi

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 309 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Akhila NairDepartment of Chemistry, Gdansk University of Technology, Gdansk, Poland.
Jozef T HaponiukDepartment of Chemistry, Gdansk University of Technology, Gdansk, Poland.
Sabu ThomasSchool of Chemical Sciences, Mahatma Gandhi University, Kottayam, India.
Sreeraj GopiDepartment of Chemistry, Gdansk University of Technology, Gdansk, Poland. Electronic address: sreerajgopi@yahoo.com.
Gdańsk University of Technology · PLMahatma Gandhi University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural carbon based quantum dots (NCDs) are an emerging class of nanomaterials in the carbon family. NCDs have gained immense acclamation among researchers because of their abundance, eco-friendly nature, aqueous solubility, the diverse functionality and biocompatibility when compared to other conventional carbon quantum dots (CDs).The presence of different functional groups on the surface of NCDs such as thiol, carboxyl, hydroxyl, etc., provides improved quantum yield, physicochemical and optical properties which promote bioimaging, sensing, and drug delivery. This review provides comprehensive knowledge about NCDs for drug delivery applications by outlining the source and rationale behind NCDs, different routes of synthesis of NCDs and the merits of adopting each method. Detailed information regarding the mechanism behind the optical properties, toxicological profile including biosafety and biodistribution of NCDs that are favourable for drug delivery are discussed. The drug delivery applications of NCDs particularly as sensing and real-time tracing probe, antimicrobial, anticancer, neurodegenerative agents are reviewed. The clinical aspects of NCDs are also reviewed as an initiative to strengthen the case of NCDs as potent drug delivery agents.

Indexed as

Drug Delivery SystemsAnimalsCarbonHumansPharmaceutical PreparationsQuantum DotsSolubilityTissue DistributionCarbonPharmaceutical PreparationsClinical statusDrug delivery applicationsNatural carbon quantum dotsOptical mechanismSynthesis

Identifiers

PMID33035830
PMCPMC7537666
OpenAlexW3092419731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.