Evidence map›Paper›PMID 33035601›Full record

ArticleAmerican journal of infection control2021

The role of close contacts of COVID-19 patients in the SARS-CoV-2 transmission: an emphasis on the percentage of nonevaluated positivity in Mexico.

Margarita L Martinez-Fierro, Jorge Ríos-Jasso, Idalia Garza-Veloz, Lucia Reyes-Veyna, Rosa Maria Cerda-Luna, Iliana Duque-Jara, Maribel Galvan-Jimenez, Leticia A Ramirez-Hernandez, Andres Morales-Esquivel, Yolanda Ortiz-Castro and 3 more

Abstract read
In one paragraph

Article in American journal of infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Margarita L Martinez-FierroMolecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Universidad Autónoma de Zacatecas, Zacatecas, Mexico. Electronic address: margaritamf@uaz.edu.mx.
Jorge Ríos-JassoMolecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Universidad Autónoma de Zacatecas, Zacatecas, Mexico.
Idalia Garza-VelozMolecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Universidad Autónoma de Zacatecas, Zacatecas, Mexico.
Lucia Reyes-VeynaDepartamento de Epidemiologia Estatal, Secretaria de Salud de Zacatecas, Zacatecas, Mexico.
Rosa Maria Cerda-LunaDepartamento de Epidemiologia, Jurisdiccion Sanitaria No.3, Secretaria de Salud de Zacatecas, Fresnillo-Zacatecas, Mexico.
Iliana Duque-JaraUnidad Medica Familiar No. 55, Instituto Mexicano del Seguro Social, Fresnillo-Zacatecas, Mexico.
Maribel Galvan-JimenezSindicatura Municipal, H. Ayuntamiento de Fresnillo, Fresnillo-Zacatecas, Mexico.
Leticia A Ramirez-HernandezUnidad Academica de Matematicas, Universidad Autonoma de Zacatecas, Zacatecas Mexico.
Andres Morales-EsquivelMolecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Universidad Autónoma de Zacatecas, Zacatecas, Mexico.
Yolanda Ortiz-CastroMolecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Universidad Autónoma de Zacatecas, Zacatecas, Mexico.
Jose R Gutierrez-CamachoMolecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Universidad Autónoma de Zacatecas, Zacatecas, Mexico.
José J Valdes-AguayoMolecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Universidad Autónoma de Zacatecas, Zacatecas, Mexico.
Jose R Vargas-RodriguezMolecular Medicine Laboratory, Unidad Academica de Medicina Humana y C.S, Universidad Autónoma de Zacatecas, Zacatecas, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the percentage of positivity of close contacts of coronavirus disease 19 (COVID-19) patients to depict the importance of asymptomatic infections in the patient-to-patient transmission of COVID-19.

methodsOne hundred subjects were included. Nineteen index COVID-19 cases and 81 traced close contacts were screened for coronavirus 2 of severe acute respiratory syndrome (SARS-CoV-2) using real-time reverse transcription-polymerase chain reaction. Immunoglobulin M and G against SARS-CoV-2 were evaluated by rapid test.

resultsThirty-four (42%) contacts in the study were positive for SARS-CoV-2. Twenty-three (67.6%) manifested less than 2 respiratory symptoms, and 5 (14.7%) remained asymptomatic. The average of positive contacts by index COVID-19 case (R

conclusionThe proportion of close contacts of COVID-19 patients infected with SARS-CoV-2 (42%) and with less than 2 or with no respiratory symptoms (82.4%) was high in the study population. A low proportion of COVID-19 patients had a positive test for antibodies against SARS-CoV-2. The screening for SARS-CoV-2 in close contacts of COVID-19 positive patients should be encouraged to avoid spreading the infection and the expansion of the disease.

Indexed as

AdultAgedCarrier StateContact TracingCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingFemaleHumansMaleMexicoMiddle AgedSARS-CoV-2Undiagnosed DiseasesYoung AdultAntibodiesAsymptomatic contactCOVID-19SARS-CoV-2

Identifiers

PMID33035601
PMCPMC7538376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.