Evidence map›Paper›PMID 33035440›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2020

Impaired left ventricular global longitudinal strain is associated with elevated left ventricular filling pressure after myocardial infarction.

Tadao Aikawa, Taro Kariya, Kelly P Yamada, Satoshi Miyashita, Olympia Bikou, Serena Tharakan, Kenneth Fish, Kiyotake Ishikawa

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Guidelines for in vivo mouse models of myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2021
    Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Lateral Planar Imaging ofAnnals of nuclear cardiology · 2024
    Article
  7. S100A9 is a functional effector of infarct wall thinning after myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tadao AikawaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York City, New York.ORCID 0000-0002-1786-0176
Taro KariyaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York City, New York.
Kelly P YamadaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York City, New York.
Satoshi MiyashitaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York City, New York.
Olympia BikouCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York City, New York.
Serena TharakanCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York City, New York.
Kenneth FishCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York City, New York.
Kiyotake IshikawaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York City, New York.ORCID 0000-0002-8287-3483
Icahn School of Medicine at Mount Sinai · US

Funding

Percutaneous Left Ventricular Unloading for Cardiogenic Shock: Beyond Acute Hemodynamic SupportR01HL139963 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Kiyotake Ishikawa · 2018 to 2026
$4.9M
NHLBI NIH HHS R01 HL139963
6 · The paper itself

Abstract

Left ventricular (LV) global longitudinal strain (GLS) has emerged as a significant prognostic marker in patients after myocardial infarction (MI). Although elevated LV filling pressure after MI might alter GLS, direct evidence for this is lacking. This study aimed to clarify the association between GLS and LV filling pressure in a large animal MI model. A total of 104 Yorkshire pigs underwent both echocardiographic and hemodynamic assessments 1-4 wk after induction of large anterior MI. GLS was measured in the apical four-chamber view using a semiautomated speckle-tracking software. LV pressure-volume relationship was invasively measured using a high-fidelity pressure-volume catheter. GLS >-14% was considered impaired. Compared with pigs with LV ejection fraction (LVEF) >40% and preserved GLS (

Indexed as

Echocardiography, Three-DimensionalStroke VolumeVentricular Function, LeftVentricular PressureAnimalsDisease Models, AnimalFemaleMaleMyocardial InfarctionPredictive Value of TestsSus scrofaglobal longitudinal strainleft ventricular filling pressureleft ventricular pressure-volume relationshipmyocardial infarction

Identifiers

PMID33035440
PMCPMC7792701
OpenAlexW3092554363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.