Evidence map›Paper›PMID 33035363›Full record

ArticleAngewandte Chemie (International ed. in English)2021

X-Ray Crystallographic Analysis of NifB with a Full Complement of Clusters: Structural Insights into the Radical SAM-Dependent Carbide Insertion During Nitrogenase Cofactor Assembly.

Wonchull Kang, Lee A Rettberg, Martin T Stiebritz, Andrew J Jasniewski, Kazuki Tanifuji, Chi Chung Lee, Markus W Ribbe, Yilin Hu

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Minimal ATP-Independent NAngewandte Chemie (International ed. in English) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. NifEN: a versatile player in nitrogenase assembly, catalysis and evolution.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Heterologous synthesis of the complex homometallic cores of nitrogenase P- and M-clusters inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Highlighting the Unique Roles of RadicalJournal of bacteriology · 2022
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wonchull KangDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, 92697-3900, USA.
Lee A RettbergDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, 92697-3900, USA.
Martin T StiebritzDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, 92697-3900, USA.
Andrew J JasniewskiDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, 92697-3900, USA.
Kazuki TanifujiDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, 92697-3900, USA.
Chi Chung LeeDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, 92697-3900, USA.
Markus W RibbeDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, 92697-3900, USA.ORCID 0000-0002-7366-1526
Yilin HuDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, 92697-3900, USA.
University of California, Irvine · US

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
Nitrogenase Assembly MechanismR01GM067626 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI RIBBE, MARKUS W · 2003 to 2024
$6.3M
Eliminating Critical Systematic Errors In Structural Biology With Next-Generation SimulationR01GM124149 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOLTON, JAMES M · 2017 to 2024
$2.5M
NIGMS NIH HHS GM67626NIGMS NIH HHS P30 GM124169NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R01 GM067626NIGMS NIH HHS R01 GM124149
6 · The paper itself

Abstract

NifB is an essential radical SAM enzyme required for the assembly of an 8Fe core of the nitrogenase cofactor. Herein, we report the X-ray crystal structures of Methanobacterium thermoautotrophicum NifB without (apo MtNifB) and with (holo MtNifB) a full complement of three [Fe

Indexed as

Crystallography, X-RayModels, MolecularMolecular StructureNitrogenaseS-AdenosylmethionineNitrogenaseS-Adenosylmethioninecarbide insertioncofactorsnitrogenasesradical SAM enzymestructural biology

Identifiers

PMID33035363
PMCPMC8410456
OpenAlexW3092528449

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.