ArticleMolecular biology and evolution2021
Differences in Postmating Transcriptional Responses between Conspecific and Heterospecific Matings in Drosophila.
Article in Molecular biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- A novel female reproductive organ differentiates insemination and postmating responses in bedbugs.Molecular biology and evolution · 2026Article
- A catalog of mRNAs transferred from males to females during mating in Drosophila arizonae and D. mojavensis.PloS one · 2026Article
- No Evidence of Sexually Antagonistic Coevolution in Drosophila Reproductive Tract Transcriptomes.Molecular biology and evolution · 2025Article
- Regional specialization, polyploidy, and seminal fluid transcripts in theProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Synthesis and Scope of the Role of Postmating Prezygotic Isolation in Speciation.Cold Spring Harbor perspectives in biology · 2024Review
- Females translate male mRNA transferred during mating.iScience · 2024Article
- Decoupled evolution of theProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Decoupled evolution of thebioRxiv : the preprint server for biology · 2023Article
- Male-derived transcripts isolated from the mated female reproductive tract in Drosophila melanogaster.G3 (Bethesda, Md.) · 2023Article
- Evolutionary Quantitative Proteomics of Reproductive Protein Divergence in Drosophila.Molecular & cellular proteomics : MCP · 2023Article
- Lactobacillus spp. in the reproductive system of female moths and mating induced changes and possible transmission.BMC microbiology · 2022Article
- Divergent evolutionary trajectories shape the postmating transcriptional profiles of conspecifically and heterospecifically mated cactophilic Drosophila females.Communications biology · 2022Article
- Experimental sexual selection reveals rapid evolutionary divergence in sex-specific transcriptomes and their interactions following mating.Molecular ecology · 2022Article
- Article
- Population biology of accessory gland-expressed de novo genes in Drosophila melanogaster.Genetics · 2022Article
- Mating Leads to a Decline in the Diversity of Symbiotic Microbiomes and Promiscuity Increased Pathogen Abundance in a Moth.Frontiers in microbiology · 2022Article
- Seminal fluid proteins induce transcriptome changes in the Aedes aegypti female lower reproductive tract.BMC genomics · 2021Article
- Gene expression and alternative splicing dynamics are perturbed in female head transcriptomes following heterospecific copulation.BMC genomics · 2021Article
- Rapid divergence of the male reproductive proteins in the Drosophila dunni group and implications for postmating incompatibilities between species.G3 (Bethesda, Md.) · 2021Article
- Pronounced Postmating Response in the Drosophila Female Reproductive Tract Fluid Proteome.Molecular & cellular proteomics : MCP · 2021Article
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3 authors at 2 institutions in 1 country.
Funding
Abstract
In many animal species, females undergo physiological and behavioral changes after mating. Some of these changes are driven by male-derived seminal fluid proteins and are critical for fertilization success. Unfortunately, our understanding of the molecular interplay between female and male reproductive proteins remains inadequate. Here, we analyze the postmating response in a Drosophila species that has evolved strong gametic incompatibility with its sister species; Drosophila novamexicana females produce only ∼1% fertilized eggs in crosses with Drosophila americana males, compared to ∼98% produced in within-species crosses. This incompatibility is likely caused by mismatched male and female reproductive molecules. In this study, we use short-read RNA sequencing to examine the evolutionary dynamics of female reproductive genes and the postmating transcriptome response in crosses within and between species. First, we found that most female reproductive tract genes are slow-evolving compared to the genome average. Second, postmating responses in con- and heterospecific matings are largely congruent, but heterospecific matings induce expression of additional stress-response genes. Some of those are immunity genes that are activated by the Imd pathway. We also identify several genes in the JAK/STAT signaling pathway that are induced in heterospecific, but not conspecific mating. While this immune response was most pronounced in the female reproductive tract, we also detect it in the female head and ovaries. These results show that the female's postmating transcriptome-level response is determined in part by the genotype of the male, and that divergence in male reproductive genes and/or traits can have immunogenic effects on females.
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