Evidence map›Paper›PMID 33035297›Full record

ArticleEuropean heart journal. Quality of care & clinical outcomes2021

Prospective follow-up in various subtypes of cardiomyopathies: insights from the ESC EORP Cardiomyopathy Registry.

Juan R Gimeno, Perry M Elliott, Luigi Tavazzi, Michal Tendera, Juan P Kaski, Cecile Laroche, Roberto Barriales-Villa, Petar Seferovic, Elena Biagini, Eloisa Arbustini and 10 more

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In one paragraph

Article in European heart journal. Quality of care & clinical outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 17 institutions in 10 countries.

Juan R GimenoInherited Cardiac Disease Unit, Hospital Clínico Universitario Virgen de la Arrixaca, Ctra. Murcia-Cartagena s/n. El Palmar, 30120 Murcia, Spain.
Perry M ElliottUniversity College London and Inherited Cardiac Diseases Unit, St. Bartholomew's Hospital, West Smithfield, Paul O'Gorman Building 72 Huntley St., London WC1E 6AG, UK.
Luigi TavazziGVM Care and Research, E.S. Health Science Foundation, Maria Cecilia Hospital, Via Corriera, 1, 48010 Cotignola, Italy.
Michal TenderaDepartment of Cardiology and Structural Heart Diseases, School of Medicine in Katowice, Medical University of Silesia, Ziolowa Street 45/47, 40-635 Katowice, Poland.
Juan P KaskiCentre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.
Cecile LarocheEURObservational Research Programme, European Society of Cardiology, 2035 Route des colles, CS 80179 Biot, 06903 Sophia-Antipolis Cedex, France.
Roberto Barriales-VillaInherited Cardiac Disease Unit, Complejo Hospitalario Universitario de A Coruña, Calle As Xubias, 84, 15006 A Coruña, Spain.
Petar SeferovicHeart Failure Center, University of Belgrade School of Medicine, Belgrade University Medical Center, Koste Todorovica 8, 11 000, Belgrade, Serbia.
Elena BiaginiDepartment of Cardiology, University of Bologna/S. Orsola-Malpighi Hospital, Via Giuseppe Massarenti, 9, 40138 Bologna, Italy.
Eloisa ArbustiniFondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi, 19, 27100 Pavia, Italy.
Luis R LopesServiço de Cardiologia, Hospital Garcia de Orta. E:P.E. Av. Torrado da Silva, 2805-267 Almada, Portugal.
Ales LinhartSecond Department of Medicine - Department of Cardiovascular Medicine, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Jens MogensenDepartment of Cardiology, Odense University Hospital, 5000 Odense C, Denmark.
Albert HagegeAssistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Cardiology Department, Sorbonne Paris Cité, INSERM U970, Paris, France.
Maria A EspinosaInherited Cardiac Disease Unit, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Aly SaadDepartment of Cardiology, Zagazig University Hospital, Zagazig, Egypt.
Aldo P MaggioniGVM Care and Research, E.S. Health Science Foundation, Maria Cecilia Hospital, Via Corriera, 1, 48010 Cotignola, Italy.
Alida L P CaforioDivision of Cardiology, Department of Cardiological Thoracic and Vascular Sciences, University of Padova, via N Giustiniani 2, 35100 Padova, Italy.
Philippe H CharronSorbonne Université, Centre de Référence des Maladies Cardiaques Héréditaires, Assistance Publique-Hôpitaux de Paris, ICAN, Inserm, UMR1166, Hôpital Pitié-Salpêtrière, Paris, France.
EORP Cardiomyopathy Registry Investigators group
European Society of Cardiology · FRInserm · FRCharles University · CZComplexo Hospitalario Universitario A Coruña · ESGreat Ormond Street Hospital · GBHospital Garcia de Orta · PTHospital General Universitario Gregorio Marañón · ESHospital Universitario Virgen de la Arrixaca · ESIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITMaria Cecilia Hospital · ITMedical University of Silesia · PLOdense University Hospital · DKPoliclinico San Matteo Fondazione · ITSt Bartholomew's Hospital · GBUniversity of Belgrade · RSUniversity of Padua · ITZagazig University · EG

Funding

Medical Research Council MR/T005181/1Medical Research Council MR/T024062/1
6 · The paper itself

Abstract

aimsThe European Society of Cardiology (ESC) European Observational Research Programme (EORP) Cardiomyopathy Registry is a prospective multinational registry of consecutive patients with cardiomyopathies. The objective of this report is to describe the short-term outcomes of adult patients (≥18 years old). METHODS AND

resultsOut of 3208 patients recruited, follow-up data at 1 year were obtained in 2713 patients (84.6%) [1420 with hypertrophic (HCM); 1105 dilated (DCM); 128 arrhythmogenic right ventricular (ARVC); and 60 restrictive (RCM) cardiomyopathies]. Improvement of symptoms (dyspnoea, chest pain, and palpitations) was globally observed over time (P < 0.05 for each). Additional invasive procedures were performed: prophylactic implantation of implantable cardioverter-defibrillator (ICD) (5.2%), pacemaker (1.2%), heart transplant (1.1%), ablation for atrial or ventricular arrhythmia (0.5% and 0.1%). Patients with atrial fibrillation increased from 28.7% to 32.2% of the cohort. Ventricular arrhythmias (VF/ventricular tachycardias) in ICD carriers (primary prevention) at 1 year were more frequent in ARVC, then in DCM, HCM, and RCM (10.3%, 8.2%, 7.5%, and 0%, respectively). Major cardiovascular events (MACE) occurred in 29.3% of RCM, 10.5% of DCM, 5.3% of HCM, and 3.9% of ARVC (P < 0.001). MACE were more frequent in index patients compared to relatives (10.8% vs. 4.4%, P < 0.001), more frequent in East Europe centres (13.1%) and least common in South Europe (5.3%) (P < 0.001). Subtype of cardiomyopathy, geographical region, and proband were predictors of MACE on multivariable analysis.

conclusionsDespite symptomatic improvement, patients with cardiomyopathies remain prone to major clinical events in the short term. Outcomes were different not only according to cardiomyopathy subtypes but also in relatives vs. index patients, and according to European regions.

Indexed as

Atrial FibrillationCardiologyCardiomyopathiesAdolescentAdultFollow-Up StudiesHumansProspective StudiesRegistriesCardiomyopathyMACEPrognosisRegistry

Identifiers

PMID33035297
PMCPMC7962774
OpenAlexW3092475691

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.