Evidence map›Paper›PMID 33035248›Full record

ArticlePloS one2020

A national study on the physical and mental health of intersex adults in the U.S.

Amy Rosenwohl-Mack, Suegee Tamar-Mattis, Arlene B Baratz, Katharine B Dalke, Alesdair Ittelson, Kimberly Zieselman, Jason D Flatt

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Pooled it
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  16. Chronic pain in transgender and gender-diverse youth: a biopsychosocial perspective.Frontiers in pain research (Lausanne, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Amy Rosenwohl-MackInstitute for Health and Aging, School of Nursing, University of California San Francisco, San Francisco, California, United States of America.ORCID 0000-0002-1961-4622
Suegee Tamar-MattisInstitute for Health and Aging, School of Nursing, University of California San Francisco, San Francisco, California, United States of America.
Arlene B BaratzinterACT: Advocates for Intersex Youth, Sudbury, Massachusetts, United States of America.
Katharine B DalkeDepartment of Psychiatry, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, Philadelphia, United States of America.
Alesdair IttelsoninterACT: Advocates for Intersex Youth, Sudbury, Massachusetts, United States of America.
Kimberly ZieselmaninterACT: Advocates for Intersex Youth, Sudbury, Massachusetts, United States of America.
Jason D FlattInstitute for Health and Aging, School of Nursing, University of California San Francisco, San Francisco, California, United States of America.ORCID 0000-0003-1244-738X
Advocates for Youth · USPenn State Milton S. Hershey Medical Center · USUniversity of California, San Francisco · USUniversity of Nevada, Las Vegas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the health of intersex adults (people with differences of sex development) in the U.S. using community-based research methods.

methodsIn July-September 2018, we conducted a national health study of intersex adults aged 18 and older in the U.S., using a survey hosted on Qualtrics. The study describes the physical and mental health experiences of intersex adults, including differences by age (18 to 39 vs. 40 and older). Questions were derived from national (Behavioral Risk Factor Surveillance System) and intersex-related health studies.

resultsA non-probability sample of 198 intersex adults completed the survey over three months. Over 43% of participants rated their physical health as fair/poor and 53% reported fair/poor mental health. Prevalent health diagnoses included depression, anxiety, arthritis, and hypertension, with significant differences by age. Nearly a third reported difficulty with everyday tasks and over half reported serious difficulties with cognitive tasks.

conclusionsTo our knowledge, this is the first national study of intersex adults in the U.S. Greater understanding of intersex health over the life course is essential. Findings highlight the need for longitudinal studies and further examination of potential health disparities experienced by intersex populations.

Indexed as

Health StatusMental HealthAdolescentAdultAgedAnxiety DisordersDepressionDisorders of Sex DevelopmentFemaleHumansLogistic ModelsMaleMiddle AgedSurveys and QuestionnairesUnited StatesYoung Adult

Identifiers

PMID33035248
PMCPMC7546494
OpenAlexW3092511514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.