Evidence map›Paper›PMID 33035217›Full record

ArticlePloS one2020

Assessment of liver and renal function tests among gasoline exposed gas station workers in Mekelle city, Tigray region, Northern Ethiopia.

Tsegay Asefaw, Mistre Wolde, Abebe Edao, Aster Tsegaye, Gebre Teklu, Feven Tesfay, Gebreslassie Gebremariam

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04815512 (Hepatorenal Dysfunctions Among Workers Exposed To Petroleum Products), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04815512 unknown statusnot on this mapstarted 2021, after this paper: background citation

Hepatorenal Dysfunctions Among Workers Exposed To Petroleum Products

TypeobservationalSponsorAssiut UniversityRan2021 to 2022Enrolled56ConditionsPetroleum Product ToxicityArmsLiver function tests., kidney function tests
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Nephroprotective potential ofFrontiers in pharmacology · 2023
    Article
  6. Article
  7. Associations Between Residential Exposure to Volatile Organic Compounds and Liver Injury Markers.Toxicological sciences : an official journal of the Society of Toxicology · 2021
    Article
  8. Occupational Liver Disease: An Underestimated Entity of Liver Injury.Indian journal of occupational and environmental medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tsegay AsefawDepartment of Medical Laboratory Science, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.ORCID 0000-0002-3295-9967
Mistre WoldeDepartment of Medical Laboratory Sciences, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.
Abebe EdaoDepartment of Medical Laboratory Sciences, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.ORCID 0000-0002-4223-4206
Aster TsegayeDepartment of Medical Laboratory Sciences, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.
Gebre TekluDepartment of Medical Laboratory Science, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Feven TesfayDepartment of Medical Laboratory Science, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.ORCID 0000-0002-7390-8234
Gebreslassie GebremariamDepartment of Medical Laboratory Science, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.ORCID 0000-0002-7359-9646
Addis Ababa University · ETMekelle University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVolatile organic compounds such as gasoline and other fuels are associated with a wide variety of deleterious health effects including liver and kidney diseases. Gasoline station workers are exposed to a mixture of hydrocarbons during dispensing. However, no published studies investigated the liver and renal function tests of gasoline station workers in Ethiopia. Therefore the aim of this study was to assess liver and renal function tests among gasoline station workers.

methodA comparative cross sectional study was conduct from January 2018 to April 2018 at Mekelle city, Tigray region, Northern Ethiopia. Liver and renal function tests were analyzed on gasoline exposed (n = 43) and controls (n = 47) by Pentra C400 automated clinical chemistry analyzer. Student independent t-test and one way-ANOVA statistical methods were employed using SPSS Ver23. P-value < 0.05 was regarded as statistically significant.

resultThe mean level of ALT, AST, Urea, creatinine, and uric acid was significantly higher among gasoline stations workers when compared to control study participants. There was also a significant increase in ALT, AST, Urea, creatinine and uric acid among gasoline stations with above 6 years exposure when compared with those exposed for ≤2 and3-6years.

conclusionThese findings suggest that increasing liver and renal parameters may be associated with exposure to gasoline and it is dependent on time of exposure to gasoline.

Indexed as

AdultBenzeneCross-Sectional StudiesEthiopiaFemaleGasolineHumansKidneyLiverMaleMiddle AgedOccupational DiseasesOccupational ExposureTransportation FacilitiesBenzeneGasoline

Identifiers

PMID33035217
PMCPMC7546501
OpenAlexW2616453653

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.