Evidence map›Paper›PMID 33034899›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2021

Gait mechanics are influenced by quadriceps strength, age, and sex after total knee arthroplasty.

Jesse C Christensen, Jacob J Capin, Lauren A Hinrichs, Moiyad Aljehani, Jennifer E Stevens-Lapsley, Joseph A Zeni

Open access · greenAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Preoperative and Post-Rehabilitation Predictors of Gait Biomechanics Six Months After Total Knee Arthroplasty.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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  6. Review
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  8. Review
  9. Article
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  13. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Jesse C ChristensenDepartment of Physical Medicine and Rehabilitation, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA.ORCID 0000-0003-1444-203X
Jacob J CapinVeterans Affairs Eastern Colorado Health Care System, Geriatric Research Education and Clinical Center, Aurora, Colorado, USA.ORCID 0000-0001-9361-3700
Lauren A HinrichsDepartment of Physical Medicine and Rehabilitation, University of Colorado, Aurora, Colorado, USA.
Moiyad AljehaniDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA.
Jennifer E Stevens-LapsleyDepartment of Physical Medicine and Rehabilitation, University of Colorado, Aurora, Colorado, USA.
Joseph A ZeniDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA.
University of Colorado Anschutz Medical Campus · USGeriatric Research Education and Clinical Center · USRutgers, The State University of New Jersey · USUmm al-Qura University · SAUniversity of Utah · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Movement Pattern Training after Total Knee ArthroplastyR56AG048943 · NIA · UNIVERSITY OF COLORADO DENVER · PI STEVENS-LAPSLEY, JENNIFER E. · 2015 to 2015
$383k
Contralateral Knee Osteoarthritis Among Older Adults after Primary Total Knee ArthroplastyF32AG066274 · NIA · UNIVERSITY OF COLORADO DENVER · PI CAPIN, JACOB J · 2019 to 2021
$94k
NCATS NIH HHS UL1 TR002538NIA NIH HHS F32 AG066274NIA NIH HHS R56 AG048943
6 · The paper itself

Abstract

Although most patients are satisfied with outcomes after total knee arthroplasty (TKA), many retain preoperative altered gait mechanics. Identifying patient characteristics associated with gait mechanics will improve rehabilitation strategies and enhance our understanding of movement disorders. Therefore, the purpose of this study was to identify which patient characteristics are related to gait mechanics in the surgical limb during walking post-TKA. Patient characteristics included age, body mass, sex, quadriceps strength, self-reported function, and knee pain. General linear regression was used to compare patient characteristics associated with gait mechanics, after controlling for gait speed, functional capacity and time from surgery. We tested 191 patients cross-sectionally at 6-24 months after primary, unilateral TKA. Quadriceps weakness in the surgical limb was associated with less peak vertical ground reaction force (PvGRF) (β = .245, p = .044), knee extension moment (β = .283, p = .049), and knee extension excursion (β = .298, p = .038). Older age (β = .168, p = .050) was associated with less PvGRF. Quadriceps strength in the nonsurgical limb (β = -.357, p = .021) was associated with greater knee extension excursion in the surgical limb. Females with TKA (β = -.276, p = .007) had less knee flexion excursion compared to males. Faster gait speed was also associated with greater PvGRF (β = .585, p < .001), knee extensor moment (β = .481, p < .001), and knee flexion excursion (β = .318, p < .001). Statement of Clinical Significance: This study showed quadriceps weakness, slower gait speed, older age and being female were related to altered gait mechanics post-TKA. These findings will help clinicians better educate patients and develop targeted interventions for improving care in patients post-TKA.

Indexed as

GaitAgedAge FactorsArthroplasty, Replacement, KneeCross-Sectional StudiesFemaleHumansKnee JointMaleMiddle AgedMuscle StrengthQuadriceps MuscleSex Factorsagegait analysisgait speedquadriceps strengthsextotal knee arthroplasty

Identifiers

PMID33034899
PMCPMC8635453
OpenAlexW3092498921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.