ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2021
Aerobic fitness and sympathetic responses to spontaneous muscle sympathetic nerve activity in young males.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- The relationship between muscle sympathetic nerve activity and serum fatty acid binding protein 4 at rest and during isometric handgrip exercise.Physiological reports · 2024Article
- The effect of cardiorespiratory fitness and habitual physical activity on cardiovascular responses to 2 h of uninterrupted sitting.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Study on the relationship between body mass index and blood pressure indices in children aged 7-17 during COVID-19.Frontiers in public health · 2024Article
- Comparison of signal-averaging and regression approaches to analyzing sympathetic transduction.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- Impact of sampling duration on spontaneous sympathetic transduction.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- Sympathetic neurohemodynamic transduction is attenuated in older males independent of aerobic fitness.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- Neural cardiovascular control is similar in female habitual exercisers and non-exercisers: a pilot study.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Article
- Flattening the sympathetic-vascular transduction curve.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- The impact of ageing and sex on sympathetic neurocirculatory regulation.Seminars in cell & developmental biology · 2021Review
- The association between habitual posture and intensity-related physical activity with sympathetic neurohemodynamic transduction in young males.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Article
- Sympathetic transduction in humans: recent advances and methodological considerations.American journal of physiology. Heart and circulatory physiology · 2021Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLower aerobic fitness increases the risk of developing hypertension. Muscle sympathetic nerve activity (MSNA) is important for the beat-by-beat regulation of blood pressure. Whether the cardiovascular consequences of lower aerobic fitness are due to augmented transduction of MSNA into vascular responses is unclear. We tested the hypothesis that aerobic fitness is inversely related to peak increases in total peripheral resistance (TPR) and mean arterial pressure (MAP) in response to spontaneous MSNA bursts in young males.
methodsRelative peak oxygen consumption (VO
resultsOverall, aerobic fitness was inversely correlated to the peak ΔTPR (0.8 ± 0.7 mmHg/l/min; R = - 0.61, P = 0.007) and ΔMAP (2.3 ± 0.8 mmHg; R = - 0.69, P < 0.001), but not with the peak ΔCO (0.2 ± 0.1 l/min; P = 0.50), MSNA burst frequency (14 ± 5 bursts/min; P = 0.43) or MSNA relative burst amplitude (65 ± 12%; P = 0.13). Heartbeats without an associated burst of MSNA did not increase TPR, MAP or CO.
conclusionAlthough unrelated to traditional MSNA characteristics, aerobic fitness was inversely associated with spontaneous sympathetic neurovascular transduction in young males. This may be a potential mechanism by which aerobic fitness modulates the regulation of arterial blood pressure through the sympathetic nervous system.
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