ArticleZeitschrift fur Rheumatologie2021
Association of urate deposition shown by ultrasound and frequent gout attacks.
Article in Zeitschrift fur Rheumatologie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Application of a Novel Ultrasound Scoring System in Assessing Disease Activity in Gouty Arthritis.Journal of inflammation research · 2026Article
- An observational study of ultrasound semiquantitative scoring for predicting the risk of gout flare.Zeitschrift fur Rheumatologie · 2024Observational
- The association between gout flares and monosodium urate burden assessed using musculoskeletal ultrasound in patients with gout.Therapeutic advances in musculoskeletal disease · 2024Article
- Elevated serum CA72-4 predicts gout flares during urate lowering therapy initiation: a prospective cohort study.Rheumatology (Oxford, England) · 2023Article
- Tongbixiao Pills Improve Gout by Reducing Uric Acid Levels and Inhibiting Inflammation.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are few data demonstrating the association between urate burden assessed by ultrasound (US) and gout flares. The aim of this study was to determine the association of urate deposition shown by US and frequent gout attacks. MATERIALS AND
methodsPatients with gout were divided into two groups according to the frequency of gout attacks in the previous 12 months: frequent (>2 attacks) and infrequent (0-2 attacks). Urate deposition in the hands, knees, and feet was assessed by US.
resultsOverall, 106 patients were enrolled in this study, of whom 32 (30.1%) had had frequent gout attacks (>2 attacks) in the previous 12 months (the average number of gout attacks was 4.7, range 3-12). Those with frequent gout attacks had significantly longer gout duration, a higher serum urate level, and more urate deposition shown by US than those with infrequent gout attacks (P < 0.05). In both univariate and logistic regression analyses, frequent gout attacks were correlated with gout duration, serum urate level, and urate deposition as shown by US (P < 0.05).
conclusionThese findings indicate that urate deposition shown by US is independently associated with frequent gout attacks. Special attention should be given to the prevention of flares in patients with an initially high urate burden as assessed by US.
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