ArticleBreast cancer research and treatment2021
Patient-reported outcomes among women with unilateral breast cancer undergoing breast conservation versus single or double mastectomy.
Article in Breast cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 20 citations in OpenAlex.
- Contralateral Prophylactic Mastectomy in Women with Unilateral Breast Cancer by Age, Race, and Tumor Subtype.Annals of surgical oncology · 2026Article
- Association Between Decision Regret and Psychosocial Outcomes Following Surgery Among Women with Unilateral Nonhereditary Breast Cancer.Annals of surgical oncology · 2026Article
- Quality of life in breast cancer survivors: a comparative analysis between breast conservative treatment (BCT) and post-mastectomy breast reconstruction (PMBR) using either autologous or prosthetic reconstruction.Updates in surgery · 2026Article
- Impact of breast reconstruction on quality of life among women after mastectomy.Journal of Taibah University Medical Sciences · 2025Article
- The Paradigm Shift From Patient to Health Consumer: 20 Years of Value Assessment in Health.Journal of medical Internet research · 2025Article
- Breast-Conserving Therapy Versus Postmastectomy Breast Reconstruction: Propensity Score-Matched Analysis.Annals of surgical oncology · 2024Article
- Patient-Reported Outcomes 10 Years After Breast-Conserving Surgery for Early-Stage Breast Cancer.Annals of surgical oncology · 2024Article
- Fear of cancer recurrence in breast cancer survivors carrying a BRCA1 or 2 genetic mutation : a cross-sectional study.Hereditary cancer in clinical practice · 2024Article
- "Peace of Mind" After Mastectomy: A Scoping Review.Annals of surgical oncology · 2024Article
- Contralateral prophylactic mastectomy in a rural population: A single-institution experience.Surgery open science · 2024Article
- Patient-Reported Outcomes in Patients Undergoing Lumpectomy With and Without Defect Closure.Annals of surgical oncology · 2024Article
- "I don't know if I understood the whole process from the beginning": A photo-elicitation exploration of the experience of mastectomy and breast reconstruction decision making.PEC innovation · 2023Article
- Timing of Chemotherapy and Patient-Reported Outcomes After Breast-Conserving Surgery and Mastectomy with Immediate Reconstruction.Annals of surgical oncology · 2023Article
- Article
- Review
- De-escalation in breast cancer surgery.NPJ breast cancer · 2022Article
- Longitudinal Study of Psychosocial Outcomes Following Surgery in Women with Unilateral Nonhereditary Breast Cancer.Annals of surgical oncology · 2021Article
- Clinical Management in BRCA Carriers with Early Breast Cancer.Cancer control : journal of the Moffitt Cancer CenterReview
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeMore women with unilateral early stage breast cancer are electing bilateral mastectomy (BM). Many cite anxiety, fear of recurrence, and certain aesthetic desires in their decision-making. Yet conflicting data exist regarding how these factors both inform and are modulated by medical decision-making, especially among women eligible for breast conservation (BCT). This study sought to assess the trajectories of women undergoing various surgical procedures for breast cancer.
methodsWe performed a prospective longitudinal study of women with unilateral, non-hereditary breast cancer who underwent BCT, unilateral mastectomy (UM), or BM. Women completed surveys before surgery and at 1, 9, and 15 months postop. Surveys included questions about treatment preferences, decisional control, the HADS-A anxiety scale, the Fear of Relapse/Recurrence Scale (FRRS), and the BREAST-Q. The Kruskal-Wallis test was used to compare outcomes between BCT, UM, and BM groups at each time point.
results203 women were recruited and 177 (87.2%) completed 15-month follow-up. Of these, 101 (57.0%) underwent BCT, 33 (18.6%) underwent UM, and 43 (24.2%) underwent BM. Generalized anxiety and FRRS scores were similar between BCT, UM, and BM groups and declined uniformly after surgery. Although baseline breast satisfaction was similar between groups, at 15 months, it was significantly lower in BM patients than in BCT patients. Women who felt "very" confident and "very" informed before surgery had lower anxiety, lower fear of recurrence, better psychosocial well-being (PSWB), and greater breast satisfaction at 15 months.
conclusionWhile patients who undergo mastectomy have less long-term breast satisfaction, all patients can expect to experience similar improvements in anxiety and PSWB. Efforts should be made to ensure that patients are informed and confident regardless of which surgery is chosen, for this is the greatest predictor of better outcomes.
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