ArticleBreast cancer research and treatment2021
Incidence and survival of inflammatory breast cancer between 1973 and 2015 in the SEER database.
Article in Breast cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Systematic Review and Meta-Analysis of Treatment Effects on Survival in Patients with Inflammatory Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2023Pooled it
- HER2DX in HER2-positive inflammatory breast cancer: correlative insights and comparative analysis with noninflammatory breast cancers.ESMO open · 2025Trial
- Reprogramming the Immune Landscape of Inflammatory Breast Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A Novel Patient-Derived Xenograft Model of Inflammatory Breast Cancer.Research square · 2026Article
- Breast Reconstruction for Inflammatory Breast Cancer: Improving Patient-Reported Outcomes in a High-Risk Population.Annals of surgical oncology · 2026Article
- Survival and Treatment Patterns in Stage III Inflammatory and Noninflammatory Breast Cancer.JAMA network open · 2026Article
- Single-cell and spatial transcriptome profiling identifies cellular heterogeneity and immunosuppressive tumor microenvironment in inflammatory breast cancer.Journal of advanced research · 2026Article
- A Retrospective Analysis of Correlations Between Shoulder Impairment and Ultrasound Lymphedema Evaluation in Breast Cancer Patients: Preliminary Results.Biomedicines · 2026Article
- Development and validation of a prognostic model for stage IV breast cancer based on primary tumor resection with machine learning methods: retrospective cohort study.Frontiers in endocrinology · 2026Article
- Barriers and facilitators of breast cancer screening services amongst black African women in high income countries: a systematic review and meta-aggregation.Discover public health · 2026Review
- Article
- Assessing the accuracy of inflammatory breast cancer self-reported diagnoses through the metastatic breast cancer project from the count me in initiative database.Breast cancer research and treatment · 2025Article
- Inter-breast Ratios of Tissue Dielectric Constant Values to Detect and Track Unilateral Breast Edema or Lymphedema.Cureus · 2025Article
- Inequality in Female Breast Cancer Relative Survival Rates between White and Black Women in the United States.Journal of racial and ethnic health disparities · 2025Article
- National trends and survival outcomes associated with non-guideline-concordant treatment of inflammatory breast cancer.Breast cancer research and treatment · 2025Article
- Database study of risk factors for breast cancer-related lymphedema: a statistical analysis of 2359 cases over 10 years.Surgery today · 2025Observational
- How to Define Inflammatory Breast Cancer: A Systematic Review.Indian journal of surgical oncology · 2025Review
- Successful unconventional precision treatment of inflammatory hormone receptor-positive breast cancer guided by molecular profiling.NPJ precision oncology · 2025Article
- Trends in Guideline-Concordant Care for Inflammatory Breast Cancer.JAMA network open · 2025Article
- Unraveling complexity and leveraging opportunities in uncommon breast cancer subtypes.NPJ breast cancer · 2025Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeInflammatory breast cancer (IBC) is an aggressive variant characterized by erythema, edema, and "peau d'orange" of the skin progressing within 6 months. We assessed the incidence and survival of IBC in the US over four decades.
methodsUsing SEER*Stat, a case list of IBC patients diagnosed between 1973 and 2015 (n = 29,718) was extracted from SEER 18 registries by using a combination of morphology, stage, and extent of disease criteria. M1 and M0 patients were included. Age-adjusted incidence rates, relative survival rates, and mean survival time were calculated. Significance was determined as non-overlapping 95% confidence intervals.
resultsThe overall incidence of IBC from 1973 to 2015 is 2.76 (2.73, 2.79) cases per 100,000 people, with white patients having an incidence rate of 2.63 (2.60, 2.67), black patients 4.52 (4.39, 4.65), and patients of other race 1.84 (1.76, 1.93). The overall IBC relative 5-year survival rate is 40.5% (39.0%, 42.0%), 42.5% (40.7%, 44.3%), and 29.9% (26.6%, 33.3%) for white patients and black patients, respectively. Patients diagnosed in 1978-1982 have a mean survival time of 62.3 (52.0, 72.6) months, while those diagnosed in 2008-2012 have mean survival time of 99.4 (96.4, 102.4) months. There is no significant difference in survival time between T4D patients and patients with other T staging and extent of disease coding consistent with clinical IBC presentation.
conclusionsIBC survival has increased over four decades. Despite the improvement in survival for all racial groups, a persistent survival disparity that has not narrowed over two decades remains between white and black patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.