Evidence map›Paper›PMID 33033953›Full record

ReviewCurrent diabetes reports2020

Do Women with Diabetes Need More Intensive Action for Cardiovascular Reduction than Men with Diabetes?

Jürgen Harreiter, Helena Fadl, Alexandra Kautzky-Willer, David Simmons

Abstract readReview
In one paragraph

Review in Current diabetes reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jürgen HarreiterGender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria. juergen.harreiter@meduniwien.ac.at.ORCID 0000-0003-2508-9403
Helena FadlDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health, Örebro University, SE 70182, Örebro, Sweden.ORCID 0000-0002-2691-7525
Alexandra Kautzky-WillerGender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria.ORCID 0000-0002-3520-4105
David SimmonsDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health, Örebro University, SE 70182, Örebro, Sweden.ORCID 0000-0003-0560-0761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis narrative review makes the case for greater efforts to reduce cardiovascular disease (CVD) risk in women with diabetes. RECENT

findingsIn a recent meta-analysis including five CVOTs of diabetes medications with 46,606 subjects, women (vs men) with type 2 diabetes had a higher relative risk for stroke (RR 1.28; 95% CI 1.09, 1.50) and heart failure (1.30; 1.21, 1.40). Prior studies found higher "within-gender" RR for CVD mortality in women with diabetes although men have an absolute higher risk. Women with prior gestational diabetes mellitus (GDM) have a 2-fold higher CVD risk than the background population. Worse CVD and CVD risk factor management in women, as well as lower female therapy adherence, contribute further to these disparities. The mechanism behind this excess risk includes biological, hormonal, socioeconomic, clinical, and behavioral factors that still require further investigation. The need for more intensive CVD reduction in women now includes more attention to screening for both incident diabetes and CVD risk factors among high-risk women.

Indexed as

Cardiovascular DiseasesDiabetes, GestationalDiabetes Mellitus, Type 2FemaleHumansMaleMass ScreeningPregnancyRisk FactorsCardiovascular diseaseCVD risk factorsDiabetes managementDiabetes mellitusGenderGestational diabetesLipidsPreventionSexSex hormones

Identifiers

PMID33033953
PMCPMC7544714

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.