Evidence map›Paper›PMID 33033952›Full record

Observational studyInternational journal of hematology2021

Analysis of determinant factors of liver fibrosis progression in ex-thalassemic patients.

Tahereh Rostami, Seyed Mostafa Monzavi, Hossein Poustchi, Ali Reza Khoshdel, Maryam Behfar, Amir Ali Hamidieh

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International journal of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Secondary Iron Overload and the Liver: A Comprehensive Review.Journal of clinical and translational hepatology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tahereh Rostami *Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Mostafa Monzavi *Department of Pediatric Stem Cell Transplantation, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Hossein PoustchiLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Ali Reza KhoshdelModern Epidemiology Research Center, AJA University of Medical Sciences, Tehran, Iran.
Maryam BehfarDepartment of Pediatric Stem Cell Transplantation, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Amir Ali HamidiehDepartment of Pediatric Stem Cell Transplantation, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. aahamidieh@tums.ac.ir.ORCID http://orcid.org/0000-0002-8935-079X
Children's Medical Center · IRTehran University of Medical Sciences · IRAja University of Medical Sciences · IR

Funding

Tehran University of Medical Sciences and Health Services TUMS-88/26
6 · The paper itself

Abstract

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) potentially renders thalassemia patients disease-free with presumably cessation of associated complications. This study analyzes the liver fibrosis status and the determinants of its progression in ex-thalassemic patients. The liver fibrosis status of 108 pediatric transfusion-dependent β-thalassemia major patients was evaluated before and one year after allo-HSCT using transient elastography (TE). All patients achieved normal hematopoiesis. In univariate analyses, not in all, but in patients developing significant post-HSCT iron overload or hepatic graft-versus-host disease (GvHD), as well as recipients of bone marrow stem cells (BMSC), significant TE increment occurred. In multivariable analyses, through a model with large effect size (Adj.R

Indexed as

Bone Marrow TransplantationHematopoietic Stem Cell TransplantationAdolescentbeta-ThalassemiaChildChild, PreschoolDisease ProgressionElasticity Imaging TechniquesFemaleGraft vs Host DiseaseHumansLiver CirrhosisMaleProspective StudiesTransplantation, HomologousBeta-thalassemiaHematopoietic stem cell transplantationHepatic fibrosisTransient elastography

Identifiers

PMID33033952
OpenAlexW3092253574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.