Evidence map›Paper›PMID 33033921›Full record

ArticleClinical oral investigations2021

Evaluation of pulsed electromagnetic field protocols in implant osseointegration: in vivo and in vitro study.

Camilla Magnoni Moretto Nunes, Camila Lopes Ferreira, Daniella Vicensotto Bernardo, Cássia Carolina Rabelo Lopes, Luma Collino, Victória Clara da Silva Lima, Daphne de Camargo Reis Mello, Luana Marotta Reis de Vasconcellos, Maria Aparecida Neves Jardini

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Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Camilla Magnoni Moretto NunesDepartment of Diagnosis and Surgery, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Av Engenheiro Francisco José Longo, 777, São Dimas, Sao Jose dos Campos, São Paulo, 12245-000, Brazil.
Camila Lopes FerreiraDepartment of Diagnosis and Surgery, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Av Engenheiro Francisco José Longo, 777, São Dimas, Sao Jose dos Campos, São Paulo, 12245-000, Brazil.
Daniella Vicensotto BernardoDepartment of Diagnosis and Surgery, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Av Engenheiro Francisco José Longo, 777, São Dimas, Sao Jose dos Campos, São Paulo, 12245-000, Brazil.
Cássia Carolina Rabelo LopesDepartment of Diagnosis and Surgery, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Av Engenheiro Francisco José Longo, 777, São Dimas, Sao Jose dos Campos, São Paulo, 12245-000, Brazil.
Luma CollinoDepartment of Diagnosis and Surgery, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Av Engenheiro Francisco José Longo, 777, São Dimas, Sao Jose dos Campos, São Paulo, 12245-000, Brazil.
Victória Clara da Silva LimaDepartment of Diagnosis and Surgery, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Av Engenheiro Francisco José Longo, 777, São Dimas, Sao Jose dos Campos, São Paulo, 12245-000, Brazil.
Daphne de Camargo Reis MelloDepartment of Bioscience and Bucal Diagnosis, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Sao Jose dos Campos, Brazil.
Luana Marotta Reis de VasconcellosDepartment of Bioscience and Bucal Diagnosis, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Sao Jose dos Campos, Brazil.
Maria Aparecida Neves JardiniDepartment of Diagnosis and Surgery, São Paulo State University (UNESP), Institute of Science and Technology of São José dos Campos, Av Engenheiro Francisco José Longo, 777, São Dimas, Sao Jose dos Campos, São Paulo, 12245-000, Brazil. maria.jardini@unesp.br.ORCID http://orcid.org/0000-0003-3229-8019
Universidade Estadual Paulista (Unesp) · BRDepartment of Aerospace Science and Technology · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001FAPESP 2018/13942-8FAPESP 2019/01669-8National Institute of Science and Technology Complex Fluids CNPq - 465259/2014-6
6 · The paper itself

Abstract

objectivesThe present study aims to evaluate two protocols of pulsed electromagnetic field (PEMF) on osseointegration and establish one that addresses ideal parameters for its use in dentistry, especially in the optimization of the implants osseointegration process. MATERIALS AND

methodsSixty male rats (Wistar) were allocated into three experimental groups: control (GC), test A (GTA, 3 h exposed), and test B (GTB, 1 h exposed). All animals received titanium implants in both tibias, and PEMF application (15 Hz, ± 1 mT, 5 days/week) occurred only in the test groups. They were euthanized at 03, 07, 21, and 45 days after PEMF therapy. Removal torque, histomorphometric measurements, three-dimensional radiographic evaluation, and in vitro biological assay analyses were performed.

resultsGTB showed better results compared with GTA in removal torque tests, in bone volume and bone mineral density, cell viability, total protein content, and mineralization nodules (p < 0.05). GTA showed better performance in trabecular bone thickness and cell proliferation compared with GTB (p < 0.05), especially at osseointegration early periods. In the histomorphometric analysis and number of trabeculae, there were no differences in the test groups.

conclusionPEMF as a biostimulator was effective in optimizing the events in bone tissue that lead to osseointegration, especially when applied for a shorter time and in the initial periods of bone healing. CLINICAL RELEVANCE: The PEMF therapy is an effective alternative method for optimizing bone healing.

Indexed as

Dental ImplantsOsseointegrationAnimalsElectromagnetic FieldsMaleRatsRats, WistarTibiaTitaniumDental ImplantsTitaniumBone-anchored implantsElectromagnetic fieldsOsseointegrationRats

Identifiers

PMID33033921
OpenAlexW3092588737

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.