Evidence map›Paper›PMID 33033637›Full record

ReviewSurgical neurology international2020

Intramedullary spinal cord cavernous malformations in the pediatric population.

Brian Fiani, Taylor Reardon, Ryne Jenkins, Claudia Covarrubias, Manraj Sekhon, Marisol Soula, Michael Kortz

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Surgical neurology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 2 countries.

Brian FianiDepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA.
Taylor ReardonKentucky College of Osteopathic Medicine, University of Pikeville, Pikeville, KY.
Ryne JenkinsCollege of Osteopathic Medicine, Western University of Health Sciences, Pomona, CA, United States.
Claudia CovarrubiasSchool of Medicine, Universidad Anáhuac Querétaro, Cto. Universidades, Santiago, de Querétaro, Mexico.
Manraj SekhonWilliam Beaumont School of Medicine, Oakland University, Rochester, Michigan.
Marisol SoulaGrossman School of Medicine, New York University, New York.
Michael KortzDepartment of Neurosurgery, University of Colorado, Aurora, Colorado, United States.
Desert Regional Medical Center · USNew York University · USOakland University · USUniversidad Anáhuac Querétaro · MXUniversity of Colorado Anschutz Medical Campus · USUniversity of Pikeville · USWestern University of Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntramedullary spinal cavernous malformations (ISCM) account for just 1% of all intramedullary pediatric spinal cord lesions. Pathologically, they are well-circumscribed vascular malformations that typically appear dark blue or reddish-brown, often coming to the spinal cord surface. With regard to the histopathology findings, ISCMs are comprised sinusoidal vascular spaces lined by a single layer of endothelial cells within a loose connective tissue stroma. As these lesions are often misdiagnosed in the pediatric population, appropriate treatment may be unduly delayed.

methodsThe authors performed an extensive review of the published literature (PubMed) focusing on ISCM in the pediatric age group.

resultsThe search yielded 17 articles exclusively pertaining to ISCM affecting the pediatric population.

conclusionHere, we reviewed the clinical, radiographic, surgical, and outcome data for the treatment of ISCM in the pediatric age groups. Notably, over 50% of pediatric patients with ISCM experienced an improvement in their neurological status after a mean postoperative follow-up duration of 4 years. Future meta-analyses are needed to highlight the potential presence of ISCM and, thereby, decrease the rate of misdiagnosis of these lesions in the pediatric population presenting with recurrent intramedullary spinal cord hemorrhages.

Indexed as

CavernomaCavernous malformationSpinal cordSpinal cord cavernous malformationsVascular malformation

Identifiers

PMID33033637
PMCPMC7538982
OpenAlexW3083654813

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.