Evidence map›Paper›PMID 33033577›Full record

ReviewComputational and structural biotechnology journal2020

The antibiotic crisis: How bacterial predators can help.

Juana Pérez, Francisco Javier Contreras-Moreno, Francisco Javier Marcos-Torres, Aurelio Moraleda-Muñoz, José Muñoz-Dorado

Open access · goldAbstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Novel Isolate ofAntibiotics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Effectiveness of predatory bacteriumOpen veterinary journal · 2025
    Article
  8. Article
  9. Article
  10. Comparative analysis of gut microbiome in Pangasionodon hypopthalmus and Labeo catla during health and disease.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Frontiers in microbiology · 2024
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Juana PérezDepartamento de Microbiología, Facultad de Ciencias, Avda. Fuentenueva s/n, Universidad de Granada, 18071 Granada, Spain.
Francisco Javier Contreras-MorenoDepartamento de Microbiología, Facultad de Ciencias, Avda. Fuentenueva s/n, Universidad de Granada, 18071 Granada, Spain.
Francisco Javier Marcos-TorresDepartment of Cell and Molecular Biology, Uppsala University, Uppsala 751 24, Sweden.
Aurelio Moraleda-MuñozDepartamento de Microbiología, Facultad de Ciencias, Avda. Fuentenueva s/n, Universidad de Granada, 18071 Granada, Spain.
José Muñoz-DoradoDepartamento de Microbiología, Facultad de Ciencias, Avda. Fuentenueva s/n, Universidad de Granada, 18071 Granada, Spain.
Universidad de Granada · ESUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discovery of antimicrobials in the past century represented one of the most important advances in public health. Unfortunately, the massive use of these compounds in medicine and other human activities has promoted the selection of pathogens that are resistant to one or several antibiotics. The current antibiotic crisis is creating an urgent need for research into new biological weapons with the ability to kill these superbugs. Although a proper solution requires this problem to be addressed in a variety of ways, the use of bacterial predators is emerging as an excellent strategy, especially when used as whole cell therapeutic agents, as a source of new antimicrobial agents by awakening silent metabolic pathways in axenic cultures, or as biocontrol agents. Moreover, studies on their prey are uncovering mechanisms of resistance that can be shared by pathogens, representing new targets for novel antimicrobial agents. In this review we discuss potential of the studies on predator-prey interaction to provide alternative solutions to the problem of antibiotic resistance.

Indexed as

Antibiotic crisisAR, antibiotic resistanceARB, antibiotic-resistant bacteriaARG, antibiotic-resistant geneBacterial predatorsBALOsBALOs, Bdellovibrio and like organismsBGC, biosynthetic gene clusterHGT, horizontal gene transferMDRB, multi-drug resistant bacteriaMyxobacteriaNRPS, nonribosomal peptide synthetaseOMV, outer membrane vesicleOSMAC, one strain many compoundsPKS, polyketide synthaseSM, secondary metaboliteWHO, World Health Organization

Identifiers

PMID33033577
PMCPMC7522538
OpenAlexW3088795002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.