Evidence map›Paper›PMID 33033519›Full record

ArticleJournal of Cancer2020

MicroRNA-29b-3p enhances radiosensitivity through modulating WISP1-mediated mitochondrial apoptosis in prostate cancer cells.

Aihong Mao, Jinzhou Tang, Deping Tang, Fang Wang, Shiqi Liao, Hongxia Yuan, Caiping Tian, Chao Sun, Jing Si, Hong Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. An overview of CCN4 (WISP1) role in human diseases.Journal of translational medicine · 2024
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. MicroRNA-29b regulates the radiosensitivity of esophageal squamous cell carcinoma by regulating the BTG2-mediated cell cycle.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Aihong MaoGansu Provincial Academic Institute for Medical Research, Lanzhou, China.
Jinzhou TangGansu Provincial Academic Institute for Medical Research, Lanzhou, China.
Deping TangSchool of Chemical & Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070, PR China.
Fang WangInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Shiqi LiaoGansu Provincial Academic Institute for Medical Research, Lanzhou, China.
Hongxia YuanGansu Provincial Academic Institute for Medical Research, Lanzhou, China.
Caiping TianGansu Provincial Academic Institute for Medical Research, Lanzhou, China.
Chao SunInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Jing SiInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Hong ZhangInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Xiaojun XiaGansu Provincial Academic Institute for Medical Research, Lanzhou, China.
Institute of Modern Physics · CNGansu Provincial Cancer Hospital Gansu Provincial Academic Instiute for Medical Research · CNGansu Provincial Hospital · CNLanzhou Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy is frequently applied for clinically localized prostate cancer while its efficacy could be significantly hindered by radioresistance. MicroRNAs (miRNAs) are important regulators in mediating cellular responses to ionizing radiation (IR), and strongly associate with radiosensitivity in many cancers. In this study, enhancement of radiosensitivity by miR-29b-3p was demonstrated in prostate cancer cell line LNCaP

Indexed as

apoptosisMiR-29b-3pprostate cancerradiosensitivityWISP1

Identifiers

PMID33033519
PMCPMC7532503
OpenAlexW3085894646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.