ArticleFood & nutrition research2020
High oleic peanuts improve parameters leading to fatty liver development and change the microbiota in mice intestine.
Article in Food & nutrition research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Effects of Peanuts and Pistachios on Gut Microbiota and Metabolic Syndrome: A Review.Foods (Basel, Switzerland) · 2023Review
- Article
- Effects of high oleic acid peanuts on mice's liver and adipose tissue metabolic parameters and gut microbiota composition.Frontiers in nutrition · 2023Article
- Metabolic and Microbiome Alterations Following the Enrichment of a High-Fat Diet With High Oleic Acid Peanuts Versus the Traditional Peanuts Cultivar in Mice.Frontiers in nutrition · 2022Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOleic-acid consumption can possibly prevent or delay metabolic diseases. In Israel, a Virginia-type peanut cultivar with a high content of oleic acid has been developed.
objectiveThis study examined the effect of consuming high oleic peanuts (D7) on the development of fatty liver compared to the standard HN strain.
designThe two peanut cultivars were added to normal diet (ND) and high-fat (HF) mouse diet. Male C57BL/6 mice were fed for 8 and 10 weeks on a 4% D7, 4% HN, or control diet. At the end of the experiments, blood and tissues were collected. Triglyceride, lipid levels, histology, and protein expression were examined. The diets' effects on intestinal microbiota were also evaluated.
resultsBoth D7 and HFD7 led to a reduction in plasma triglycerides. Lipids, triglycerides, and free fatty acids in the liver were low in diets containing D7. Additionally, CD36 expression decreased in the D7 group. Consumption of D7 led to higher
conclusionThese findings suggest that consumption of peanuts high in oleic acid (D7) may have the potential to delay primary fatty liver symptoms.
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