ArticleScientific reports2020
Evidence for and against deformed wing virus spillover from honey bees to bumble bees: a reverse genetic analysis.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Differential expression of neuronal function genes follows a tissue-specific temporal dynamic during Deformed Wing Virus infection in honeybees.Scientific reports · 2026Article
- Patterns of viral prevalence and load show independent circulation of some honey bee viruses in wild bees.Scientific reports · 2026Article
- Genetic diversity of Apis mellifera filamentous virus in bees sampled in the USA and Jamaica.Archives of virology · 2026Article
- Article
- Comprehensive virome analysis ofFrontiers in insect science · 2026Article
- Bumble Bees and Honey Bees on Islands Harbour Reduced Viral Species Richness, Yet Honey Bee Populations Are Dominated by a Deformed Wing Virus Recombinant.Molecular ecology · 2025Article
- Distinct virome compositions and lack of viral diversification indicate that viral spillover is a dead-end between the western honey bee and the common eastern bumblebee.Communications biology · 2025Article
- Host ecology and phylogeny shape the temporal dynamics of social bee viromes.Nature communications · 2025Article
- Avoiding the tragedies of parasite tolerance in Darwinian beekeeping.Proceedings. Biological sciences · 2025Review
- The Role of Pathogens in Bumblebee Decline: A Review.Pathogens (Basel, Switzerland) · 2025Review
- Caught in the act: the invasion of a viral vector changes viral prevalence and titre in native honeybees and bumblebees.Biology letters · 2024Article
- Host Barriers Limit Viral Spread in a Spillover Host: A Study of Deformed Wing Virus in the BumblebeeViruses · 2024Article
- Nursing Honeybee Behavior and Sensorial-Related Genes Are Altered by Deformed Wing Virus Variant A.Insects · 2024Article
- A semi-automated and high-throughput approach for the detection of honey bee viruses in bee samples.PloS one · 2024Article
- Doomed drones? Using passage experiments and mathematical modelling to determine Deformed wing virus population dynamics in male honeybees.Proceedings. Biological sciences · 2023Article
- All together now: Geographically coordinated miticide treatment benefits honey bee health.The Journal of applied ecology · 2023Article
- CRISPR-induced DNA reorganization for multiplexed nucleic acid detection.Nature communications · 2023Article
- Molecular Detection and Phylogenetic Analysis of Deformed Wing Virus and Sacbrood Virus Isolated from Pollen.Veterinary sciences · 2023Article
- Endosymbionts that threaten commercially raised and wild bumble bees (Journal of pollination ecology · 2023Article
- An Evidence-based rationale for a North American commercial bumble bee clean stock certification program.Journal of pollination ecology · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Deformed wing virus (DWV) is a persistent pathogen of European honey bees and the major contributor to overwintering colony losses. The prevalence of DWV in honey bees has led to significant concerns about spillover of the virus to other pollinating species. Bumble bees are both a major group of wild and commercially-reared pollinators. Several studies have reported pathogen spillover of DWV from honey bees to bumble bees, but evidence of a sustained viral infection characterized by virus replication and accumulation has yet to be demonstrated. Here we investigate the infectivity and transmission of DWV in bumble bees using the buff-tailed bumble bee Bombus terrestris as a model. We apply a reverse genetics approach combined with controlled laboratory conditions to detect and monitor DWV infection. A novel reverse genetics system for three representative DWV variants, including the two master variants of DWV-type A and B-was used. Our results directly confirm DWV replication in bumble bees but also demonstrate striking resistance to infection by certain transmission routes. Bumble bees may support DWV replication but it is not clear how infection could occur under natural environmental conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.