Evidence map›Paper›PMID 33033229›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Heterologous microProtein expression identifies LITTLE NINJA, a dominant regulator of jasmonic acid signaling.

Shin-Young Hong, Bin Sun, Daniel Straub, Anko Blaakmeer, Lorenzo Mineri, Jonas Koch, Henrik Brinch-Pedersen, Inger B Holme, Meike Burow, Hans Jørgen Lyngs Jørgensen and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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  14. Microproteins - lost in translation.Nature chemical biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Shin-Young HongDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.ORCID 0000-0003-3031-2753
Bin SunDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.ORCID 0000-0003-1201-762X
Daniel StraubDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.ORCID 0000-0002-2553-0660
Anko BlaakmeerDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.ORCID 0000-0002-1834-2573
Lorenzo MineriDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.
Jonas KochDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.ORCID 0000-0002-2080-6293
Henrik Brinch-PedersenNovoCrops Centre, University of Copenhagen, 1871 Frederiksberg C, Denmark.ORCID 0000-0002-9773-8903
Inger B HolmeDepartment of Molecular Biology and Genetics, Research Centre Flakkebjerg, Aarhus University, 4200 Slagelse, Denmark.ORCID 0000-0001-5008-0086
Meike BurowDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.ORCID 0000-0002-2350-985X
Hans Jørgen Lyngs JørgensenDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.ORCID 0000-0002-5902-6550
M Mar AlbàEvolutionary Genomics Group, Research Programme on Biomedical Informatics, Hospital del Mar Research Institute, Universitat Pompeu Fabra, 08003 Barcelona, Spain.ORCID 0000-0002-7963-7375
Stephan WenkelDepartment of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark; wenkel@plen.ku.dk.ORCID 0000-0001-5764-9423
University of Copenhagen · DKAarhus University · DKInstitució Catalana de Recerca i Estudis Avançats · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroProteins are small, often single-domain proteins that are sequence-related to larger, often multidomain proteins. Here, we used a combination of comparative genomics and heterologous synthetic misexpression to isolate functional cereal microProtein regulators. Our approach identified LITTLE NINJA (LNJ), a microProtein that acts as a modulator of jasmonic acid (JA) signaling. Ectopic expression of

Indexed as

Gene Expression Regulation, PlantArabidopsisCyclopentanesGene Expression ProfilingHordeumOryzaOxylipinsPlant Growth RegulatorsPlant ProteinsPlants, Genetically ModifiedProtein IsoformsRepressor ProteinsSignal TransductionCyclopentanesjasmonic acidOxylipinsPlant Growth RegulatorsPlant ProteinsProtein IsoformsRepressor Proteinsbranchingjasmonic acidmicroProteins

Identifiers

PMID33033229
PMCPMC7584889
OpenAlexW3092392322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.