Evidence map›Paper›PMID 33033227›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Multiscale imaging of basal cell dynamics in the functionally mature mammary gland.

Alexander J Stevenson, Gilles Vanwalleghem, Teneale A Stewart, Nicholas D Condon, Bethan Lloyd-Lewis, Natascia Marino, James W Putney, Ethan K Scott, Adam D Ewing, Felicity M Davis

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
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  6. Article
  7. Breast Morphogenesis: From Normal Development to Cancer.Advances in experimental medicine and biology · 2025
    Review
  8. Article
  9. Deformable microlaser force sensing.Light, science & applications · 2024
    Article
  10. Article
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  12. Mapping uterine calcium dynamics during the ovulatory cycle in live mice.bioRxiv : the preprint server for biology · 2024
    Article
  13. Intracellular CaiScience · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. From calcium imaging to graph topology.Network neuroscience (Cambridge, Mass.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Alexander J StevensonFaculty of Medicine, Mater Research Institute, The University of Queensland, Brisbane, QLD 4102, Australia.ORCID 0000-0001-5909-066X
Gilles VanwalleghemQueensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-6188-9582
Teneale A StewartFaculty of Medicine, Mater Research Institute, The University of Queensland, Brisbane, QLD 4102, Australia.ORCID 0000-0003-4837-9315
Nicholas D CondonInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-1833-1129
Bethan Lloyd-LewisSchool of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, United Kingdom.ORCID 0000-0001-6511-1818
Natascia MarinoSusan G. Komen Tissue Bank at IU Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202.ORCID 0000-0001-6771-8963
James W PutneyNational Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709.
Ethan K ScottQueensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0003-3150-9216
Adam D EwingFaculty of Medicine, Mater Research Institute, The University of Queensland, Brisbane, QLD 4102, Australia.ORCID 0000-0002-4544-994X
Felicity M DavisFaculty of Medicine, Mater Research Institute, The University of Queensland, Brisbane, QLD 4102, Australia; f.davis@uq.edu.au.ORCID 0000-0001-9112-118X
Translational Research Institute · AUThe University of Queensland · AUIndiana University Health · USNational Institutes of Health · USUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammary epithelium is indispensable for the continued survival of more than 5,000 mammalian species. For some, the volume of milk ejected in a single day exceeds their entire blood volume. Here, we unveil the spatiotemporal properties of physiological signals that orchestrate the ejection of milk from alveolar units and its passage along the mammary ductal network. Using quantitative, multidimensional imaging of mammary cell ensembles from GCaMP6 transgenic mice, we reveal how stimulus evoked Ca

Indexed as

Calcium SignalingMilk EjectionAnimalsEpithelial CellsHumansIntravital MicroscopyMammary Glands, AnimalMammary Glands, HumanMiceMice, TransgenicMyosin Light ChainsMyosin Light Chainscalcium signalingGCaMP6lactationmammary glandoxytocin

Identifiers

PMID33033227
PMCPMC7604439
OpenAlexW3092221337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.