SynthesisBMJ open2020
Incidence of sudden cardiac death in the young: a systematic review.
Synthesis in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Sex Differences in the Incidence of Sudden Cardiac Arrest/Death in Competitive Athletes: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Redefining the Post-Mortem Investigation of Sudden Cardiac Death: Systematic Cardiac MR with Macroscopic and Histological Correlation from the Friuli Venezia Giulia Regional Registry.Diagnostics (Basel, Switzerland) · 2026Article
- Incidence and clinical manifestations of sudden death in young adults: a two-decade, nationwide, retrospective, cross-sectional study.Resuscitation plus · 2026Article
- Sudden cardiac arrest in young adults: A comprehensive systematic review of epidemiology, aetiology and preventive strategies.Heart international · 2026Review
- Epidemiology of paediatric inherited arrhythmogenic diseases under "Real World" conditions: findings from a 10-year longitudinal study in Eastern Austria.European journal of pediatrics · 2025Article
- Sudden cardiac death in a young athlete due to anomalous origin of both coronaries from a common ostium.Forensic science, medicine, and pathology · 2025Article
- Moderate Kidney Dysfunction Independently Increases Sudden Cardiac Arrest Risk: A Community-Based Study.Journal of the American Heart Association · 2025Article
- Recommendations for cardiac screening and emergency action planning in youth football: a FIFA consensus statement.British journal of sports medicine · 2025Article
- Rising out-of-hospital mortality in Canada during 2020‒2022: A striking impact observed among young adults.Canadian journal of public health = Revue canadienne de sante publique · 2025Article
- Preparticipation Cardiovascular Screening of Athletes: Current Controversies and Challenges for the Future.Diagnostics (Basel, Switzerland) · 2024Review
- International Criteria for Reporting Study Quality for Sudden Cardiac Arrest/Death Tool.Journal of the American Heart Association · 2024Article
- Post-mortem genetic analysis of sudden unexplained death in a young cohort: a whole-exome sequencing study.International journal of legal medicine · 2023Article
- Sudden cardiac arrest in athletes and strategies to optimize preparedness.Clinical cardiology · 2023Review
- Sudden Cardiac Death: A Systematic Review.Cureus · 2023Review
- Review
- The safety of sports in children with inherited arrhythmia substrates.Frontiers in pediatrics · 2023Review
- Sudden Cardiac Death in Young Individuals: A Current Review of Evaluation, Screening and Prevention.Journal of clinical medicine research · 2023Review
- Eosinophilic Infiltration of the Sino-Atrial Node in Sudden Cardiac Death Caused by Long QT Syndrome.International journal of molecular sciences · 2022Article
- From diagnostic testing to precision medicine: the evolving role of genomics in cardiac channelopathies and cardiomyopathies in children.Current opinion in genetics & development · 2022Review
- Sudden Cardiac Arrest in the Paediatric Population.CJC pediatric and congenital heart disease · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo summarise studies describing incidence of sudden cardiac death in a general population of young individuals to inform screening policy.
designSystematic review. DATA SOURCES: Database searches of MEDLINE, EMBASE and the Cochrane library (all inception to current) on 29 April 2019 (updated 16 November 2019), and forward/backward citation tracking of eligible studies. STUDY ELIGIBILITY CRITERIA: All studies that reported incidence of sudden cardiac death in young individuals (12-39 years) in a general population, with no restriction on language or date. Planned subgroups were incidence by age, sex, race and athletic status (including military personnel). DATA EXTRACTION: Two reviewers independently assessed study eligibility, extracted study data and assessed risk of bias using the Joanna Briggs Institute critical appraisal checklist for prevalence studies. ANALYSIS: Reported incidence of sudden cardiac death in the young per 100 000 person-years.
results38 studies that reported incidence across five continents. We identified substantial heterogeneity in population, sudden cardiac death definition, and case ascertainment methods, precluding meta-analysis. Median reported follow-up years was 6.97 million (IQR 2.34 million-23.70 million) and number of sudden cardiac death cases was 64 (IQR 40-251). In the general population, the median of reported incidence was 1.7 sudden cardiac death per 100 000 person-years (IQR 1.3-2.6, range 0.75-11.9). Most studies (n=14, 54%) reported an incidence between one and two cases per 100 000 person-years. Incidence was higher in males and older individuals.
conclusionsThis systematic review identified variability in the reported incidence of sudden cardiac death in the young across studies. Most studies reported an incidence between one and two cases per 100 000 person-years. PROSPERO REGISTRATION NUMBER: CRD42019120563.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.