Evidence map›Paper›PMID 33033026›Full record

ArticleBMJ open2020

Protocol of a multicentre, prospective cohort study that evaluates cost-effectiveness of two perioperative care strategies for potential obstructive sleep apnoea in morbidly obese patients undergoing bariatric surgery.

Sophie L van Veldhuisen, Kim Kuppens, Christel A L de Raaff, Marinus J Wiezer, Steve M M de Castro, Ruben N van Veen, Dingeman J Swank, Ahmet Demirkiran, Evert-Jan G Boerma, Jan-Willem M Greve and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Sophie L van VeldhuisenDepartment of Surgery / Vitalys Clinic, Rijnstate Ziekenhuis, Arnhem, The Netherlands svanveldhuisen@rijnstate.nl s.l.vanveldhuisen@gmail.com.ORCID 0000-0002-0044-8441
Kim KuppensDepartment of Pulmonary Medicine, St. Antonius Ziekenhuis, Nieuwegein, The Netherlands.
Christel A L de RaaffDepartment of Surgery, Albert Schweitzer Ziekenhuis, Dordrecht, The Netherlands.
Marinus J WiezerDepartment of Surgery, St. Antonius Ziekenhuis, Nieuwegein, The Netherlands.
Steve M M de CastroDepartment of Surgery, OLVG, location West, Amsterdam, The Netherlands.
Ruben N van VeenDepartment of Surgery, OLVG, location West, Amsterdam, The Netherlands.
Dingeman J SwankDepartment of Surgery, Dutch Obesity Clinic (Nederlandse Obesitas Kliniek), The Hague, The Netherlands.
Ahmet DemirkiranDepartment of Surgery, Rode Kruis Ziekenhuis, Beverwijk, The Netherlands.
Evert-Jan G BoermaDepartment of Surgery, Zuyderland Medisch Centrum, Heerlen, The Netherlands.
Jan-Willem M GreveDepartment of Surgery, Zuyderland Medisch Centrum, Heerlen, The Netherlands.
Francois M H van DielenDepartment of Surgery, Maxima Medisch Centrum, Eindhoven, The Netherlands.
Geert W J FrederixDepartment of Public Health, Julius Center Research Program Methodology, Universitair Medisch Centrum Utrecht, Utrecht, The Netherlands.
Eric J HazebroekDepartment of Surgery / Vitalys Clinic, Rijnstate Ziekenhuis, Arnhem, The Netherlands.
OLVG · NLRijnstate Hospital · NLSt. Antonius Ziekenhuis · NLAlbert Schweitzer Ziekenhuis · NLMaastricht University · NLNederlandse Obesitas Kliniek · NLRadboud University Nijmegen · NLRode Kruis Ziekenhuis · NLUniversity Medical Center Utrecht · NLZuyderland Medisch Centrum · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite the high prevalence of obstructive sleep apnoea (OSA) in obese patients undergoing bariatric surgery, OSA is undiagnosed in the majority of patients and thus untreated. While untreated OSA is associated with an increased risk of preoperative and postoperative complications, no evidence-based guidelines on perioperative care for these patients are available. The aim of the POPCORN study ( METHODS AND ANALYSIS: In this multicentre observational cohort study, data from 1380 patients who will undergo bariatric surgery will be collected. Patients will receive either postoperative care with pulse oximetry monitoring and supplemental oxygen during the first postoperative night, or care that includes preoperative PG and CPAP treatment in case of moderate or severe OSA. Local protocols for perioperative care in each participating hospital will determine into which cohort a patient is placed. The primary outcome is cost-effectiveness, which will be calculated by comparing all healthcare costs with the quality-adjusted life-years (QALYs, calculated using EQ-5D questionnaires). Secondary outcomes are mortality, complications within 30 days after surgery, readmissions, reoperations, length of stay, weight loss, generic quality of life (QOL), OSA-specific QOL, OSA symptoms and CPAP adherence. Patients will receive questionnaires before surgery and 1, 3, 6 and 12 months after surgery to report QALYs and other patient-reported outcomes. ETHICS AND DISSEMINATION: Approval from the Medical Research Ethics Committees United was granted in accordance with the Dutch law for Medical Research Involving Human Subjects Act (WMO) (reference number W17.050). Results will be submitted for publication in peer-reviewed journals and presented at (inter)national conferences. TRIAL REGISTRATION NUMBER: NTR6991.

Indexed as

Bariatric SurgeryObesity, MorbidSleep Apnea, ObstructiveCohort StudiesContinuous Positive Airway PressureCost-Benefit AnalysisHumansMulticenter Studies as TopicObservational Studies as TopicOximetryOxygenPerioperative CareProspective StudiesQuality of LifeOxygenadult surgeryrespiratory medicine (see thoracic medicine)sleep medicine

Identifiers

PMID33033026
PMCPMC7542938
OpenAlexW3092395613

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.