Evidence map›Paper›PMID 33032633›Full record

ArticleEuropean journal of medical research2020

Heart rate at discharge in patients with acute decompensated heart failure is a predictor of mortality.

Thomas Vollmert, Martin Hellmich, Natig Gassanov, Fikret Er, Seyrani Yücel, Erland Erdmann, Evren Caglayan

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Thomas VollmertDepartment III for Internal Medicine, University of Cologne, Cologne, Germany.
Martin HellmichInstitute of Medical Statistics and Computational Biology (IMSB), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Natig GassanovDepartment II for Internal Medicine, Klinikum Idar-Oberstein, Idar-Oberstein, Germany.
Fikret ErDepartment of Cardiology and Electrophysiology, Klinikum Gütersloh, Gütersloh, Germany.
Seyrani YücelDepartment of Cardiology, University-Medicine Rostock, Rostock, Germany.
Erland ErdmannDepartment III for Internal Medicine, University of Cologne, Cologne, Germany.
Evren CaglayanDepartment of Cardiology, University-Medicine Rostock, Rostock, Germany. evren.caglayan@med.uni-rostock.de.ORCID http://orcid.org/0000-0002-5707-8285
University of Cologne · DEUniversity of Rostock · DEArvato · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsHeart failure is a syndrome with increasing prevalence in concordance with the aging population and better survival rates from myocardial infarction. Morbidity and mortality are high in chronic heart failure patients, particularly in those with hospital admission for acute decompensation. Several risk stratification tools and score systems have been established to predict mortality in chronic heart failure patients. However, identification of patients at risk with easy obtainable clinical factors that can predict mortality in acute decompensated heart failure (ADHF) are needed to optimize the care-path. METHODS AND

resultsWe retrospectively analyzed electronic medical records of 78 patients with HFrEF and HFmrEF who were hospitalized with ADHF in the Heart Center of the University Hospital Cologne in the year 2011 and discharged from the ward after successful treatment. 37.6 ± 16.4 months after index hospitalization 30 (38.5%) patients had died. This mortality rate correlated well with the calculated predicted survival with the Seattle Heart Failure Model (SHFM) for each individual patient. In our cohort, we identified elevated heart rate at discharge as an independent predictor for mortality (p = 0.016). The mean heart rate at discharge was lower in survived patients compared to patients who died (72.5 ± 11.9 vs. 79.1 ± 11.2 bpm. Heart rate of 77 bpm or higher was associated with an almost doubled mortality risk (p = 0.015). Heart rate elevation of 5 bpm was associated with an increase of mortality of 25% (p = 0.022).

conclusionsPatients hospitalized for ADHF seem to have a better prognosis, when heart rate at discharge is < 77 bpm. Heart rate at discharge is an easily obtainable biomarker for risk prediction of mortality in HFrEF and HFmrEF patients treated for acute cardiac decompensation. Taking into account this parameter could be useful for guiding treatment strategies in these high-risk patients. Prospective data for validation of this biomarker and specific intervention are needed.

Indexed as

Heart RateAgedAged, 80 and overFemaleHeart FailureHumansMaleMiddle AgedPatient DischargeAcute decompensated heart failureHeart rate at dischargeHFmrEFHFrEFMortality

Identifiers

PMID33032633
PMCPMC7545571
OpenAlexW3091984587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.