Evidence map›Paper›PMID 33032603›Full record

ArticleRespiratory research2020

Dexamethasone rescues TGF-β1-mediated β

Elena Chung, Christie A Ojiaku, Gaoyuan Cao, Vishal Parikh, Brian Deeney, Shengjie Xu, Serena Wang, Reynold A Panettieri, Cynthia Koziol-White

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Rhinovirus C15 Attenuates Relaxation and cAMP Production in Human Airways and Smooth Muscle.American journal of respiratory cell and molecular biology · 2023
    Article
  3. Article
  4. Article
  5. Carbocistein improves airway remodeling in asthmatic mice.American journal of translational research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Elena ChungDepartment of Pharmacology and Toxicology, School of Pharmacy, EOHSI, Rutgers University, Piscataway, NJ, USA.
Christie A OjiakuRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Gaoyuan CaoRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Vishal ParikhRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Brian DeeneyRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Shengjie XuDepartment of Pharmacology and Toxicology, School of Pharmacy, EOHSI, Rutgers University, Piscataway, NJ, USA.
Serena WangRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Reynold A PanettieriRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA. rp856@rbhs.rutgers.edu.
Cynthia Koziol-WhiteRutgers Institute for Translational Medicine and Science, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
Rutgers, The State University of New Jersey · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
Project 4 - OGR1- and TSPO- dependent mechanisms mediated by benzodiazepines affecting ASM contractionP01HL114471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LIGGETT, STEPHEN B · 2013 to 2023
$23.9M
NCATS NIH HHS UL1 TR003017NHLBI NIH HHS P01 HL114471NHLBI NIH HHS P01-HL114471NIEHS NIH HHS P30 ES005022NIH HHS UL1TR003017
6 · The paper itself

Abstract

Glucocorticoids (GCs) and β

Indexed as

Anti-Inflammatory AgentsCyclic Nucleotide Phosphodiesterases, Type 4DexamethasoneDose-Response Relationship, DrugGene Expression Regulation, EnzymologicHumansMyocytes, Smooth MusclePhosphodiesterase 4 InhibitorsReceptors, Adrenergic, beta-2Respiratory MucosaTracheaTransforming Growth Factor beta1Anti-Inflammatory AgentsCyclic Nucleotide Phosphodiesterases, Type 4DexamethasonePhosphodiesterase 4 InhibitorsReceptors, Adrenergic, beta-2TGFB1 protein, humanTransforming Growth Factor beta1Airway remodelingBronchodilationGlucocorticoidsSevere asthma

Identifiers

PMID33032603
PMCPMC7545943
OpenAlexW3092369223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.