Trial reportRespiratory research2020
Obstructive sleep apnea as a risk factor for primary open angle glaucoma and ocular hypertension in a monocentric pilot study.
Trial report in Respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Microvascular changes in the macular area in patients with obstructive sleep apnoea syndrome compared to controls: A systematic review and meta-analysis.Eye (London, England) · 2026Pooled it
- Assessing physical activity and sleep patterns in glaucoma using wearable devices.The British journal of ophthalmology · 2026Article
- Structured Reporting in Sleep Medicine.Diagnostics (Basel, Switzerland) · 2025Article
- Anatomic Features of the Nasal and Pharyngeal Region Do Not Influence PAP Therapy Response.International journal of environmental research and public health · 2023Article
- Obsructive sleep apnea syndrome: is it a risk factor for ocular surface disease and ocular comorbidities?International ophthalmology · 2023Article
- Serum Ferritin Levels in Severe Obstructive Sleep Apnea.Diagnostics (Basel, Switzerland) · 2023Article
- The Need for Glaucoma Management in Glaucoma Patients with Concurrent Obstructive Sleep Apnea: A Population-Based Cohort Study.Biomedicines · 2023Article
- Short-Term Outcome of Unilateral Inspiration-Coupled Hypoglossal Nerve Stimulation in Patients with Obstructive Sleep Apnea.International journal of environmental research and public health · 2022Article
- A Narrative Review of the Association between Obstructive Sleep Apnea and Glaucoma in Adults.International journal of molecular sciences · 2022Review
- Obstructive Sleep Apnea in Patients with Head and Neck Cancer-More than Just a Comorbidity?Medicina (Kaunas, Lithuania) · 2021Review
- Ocular Complications of Obstructive Sleep Apnea.Journal of clinical medicine · 2021Review
- Associations of sleep apnoea with glaucoma and age-related macular degeneration: an analysis in the United Kingdom Biobank and the Canadian Longitudinal Study on Aging.BMC medicine · 2021Article
- Obstructive Sleep Apnea is Related with the Risk of Retinal Vein Occlusion.Nature and science of sleep · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBoth glaucoma and obstructive sleep apnea (OSA) are widespread diseases. OSA may presumably partly cause or worsen glaucoma, although the etiopathogenesis is unclear. Here we analyze for the first time the possible association between different glaucoma phenotypes and OSA.
methods110 patients (47 females, 63 males; median age 64.3 years, median BMI 26.62 kg/m
resultsThere was no strong correlation between IOP or MD and AHI. BMI, age and gender did not differ between groups. Significant differences between POAG and LTG were found for all HSAT parameters. The AHI showed the most prominent group difference (Wilcoxon-Kruskal-Wallis rank sum test was highly significant with chi
conclusionAlthough physical endpoints, such as MD and IOP, do not correlate with AHI, there was a strong correlation between the POAG and OH clinical glaucoma phenotypes and the AHI. Further studies should investigate the necessity to test routine screening for OSA by HSAT in patients with diagnosed POAG and OH. Besides, some characteristics of LTG differed widely from other glaucoma types and controls. LTG patients had a significantly lower rate of OSA compared to other glaucoma types and even controls. This might be due to a different pathogenesis of LTG.
trial registrationRetrospectively registered at DRKS ( nr. S00021201 ) on April 9th 2020.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.