Evidence map›Paper›PMID 33032568›Full record

ArticleBMC musculoskeletal disorders2020

Morphological signs of connective tissue dysplasia as predictors of frequent post-exercise musculoskeletal disorders.

V N Nikolenko, M V Oganesyan, A D Vovkogon, Yu Cao, A A Churganova, M A Zolotareva, E E Achkasov, M V Sankova, N A Rizaeva, M Y Sinelnikov

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

V N NikolenkoFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
M V OganesyanFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
A D VovkogonFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
Yu CaoFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
A A ChurganovaFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
M A ZolotarevaFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
E E AchkasovFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
M V SankovaFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
N A RizaevaFirst Moscow State Medical University named after I.M.Sechenov (Sechenov University), st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia.
M Y SinelnikovInstitute for Regenerative Medicine, Sechenov University, st. Trubetskaya, 8, bld. 2, 119991, Moscow, Russia. rektorat@sechenov.ru.ORCID http://orcid.org/0000-0002-0862-6011
Sechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConnective tissue dysplasia (CTD) is a risk factor for musculoskeletal disorders. Changes caused by disorganization of collagen and elastin fibers lead to the inability of withstanding heavy mechanical stress. In clinical practice, diagnosis of these disorders depends on physical and anthropomorphic evaluation.

methodsForty-eight patients with frequent post-exercise musculoskeletal disorders were evaluated for CTD. The control group included 36 healthy participants. Both groups were evaluated via therapeutic examination with assessment of anthropometric indicators and physical-physiological evaluation, surveying and gathering of anamnesis. Based on testing results, study participants were evaluated on CTD presence and risk factors.

resultsAll experimental group patients had connective tissue dysplasia of moderate and severe degree, with a total score of 49.44 ± 13.1. Certain morphological characteristics showed prevalence, allowing to determine pathognomonic predictors of high predisposition to frequent post-exercise musculoskeletal disorders. Back pain (100%), asthenic syndrome and kyphotic spinal deformation (75%), high gothic palate, hypermobility of joints and the auricles, excessive elasticity (63%), varicose veins of the lower extremities (56%) and hemorrhoids (56%), changes in the shape of the legs and temporomandibular joint (50%) showed to be significant clinical factors indicating possible connective tissue dysplasia.

conclusionsThe presence of these diagnostically significant morphological signs of CTD in humans is a pathognomonic predictor of a high predisposition to frequent injuries. Their early detection helps promote proper appointment of adequate physical activity regimen and develop treatment for the underlying cause.

Indexed as

Connective Tissue DiseasesMusculoskeletal DiseasesConnective TissueExerciseHumansSyndromeConnective tissue dysplasiaMorphological predictorsPost-exercise musculoskeletal disorders

Identifiers

PMID33032568
PMCPMC7545870
OpenAlexW3092441669

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.