Trial reportBMC geriatrics2020
A physical activity program versus usual care in the management of quality of life for pre-frail older adults with chronic pain: randomized controlled trial.
Trial report in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04045535 (Effectiveness of a Physical Activity Intervention in the Quality of Life of Pre-frail Older Adults Aged 65 Years or Over With Chronic Pain. Randomized Controlled, Multicenter and Pragmatic Trial in Primary Care.), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of a Physical Activity Intervention in the Quality of Life of Pre-frail Older Adults Aged 65 Years or Over With Chronic Pain. Randomized Controlled, Multicenter and Pragmatic Trial in Primary Care.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- The effectiveness of exercise interventions on muscle strength and balance function in pre-frail older adults: a systematic review and Bayesian network meta-analysis.Frontiers in public health · 2025Pooled it
- Community-based exercises improve health status in pre-frail older adults: A systematic review with meta-analysis.BMC geriatrics · 2024Pooled it
- Effects of physical training on depression and related quality of life in pre-frail and frail older adults: a systematic review and meta-analysis.The journal of nutrition, health & aging · 2024Pooled it
- Effects of proactive healthcare on pain, physical and activities of daily living functioning in vulnerable older adults with chronic pain: a pragmatic clinical trial with one- and two-year follow-up.European geriatric medicine · 2024Trial
- Article
- Impact of Face-to-Face and Online Mindfulness-Based Public Health Interventions on Health-Related Quality of Life in Older People: A Comparative Study.International journal of environmental research and public health · 2025Article
- Effects of a Salutogenic Model-Based Frailty Prevention Program (SAFRAPP) in pre-frail women: a randomized controlled trial.BMC nursing · 2025Article
- Enhancing quality of life for activity-limited older adults in Sri Lanka: a need-based caregiver education intervention study.BMC geriatrics · 2025Article
- Comparing Frailty Status Among Clusters Identified Based on EQ-5D-5L Dimensions in Older Patients with Chronic Low Back Pain.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- The relationship between chronic pain and health-related quality of life: the mediating roles of frailty and depression in chronic disease patients.Frontiers in public health · 2025Article
- Physical activity and nutrient intake levels according to grip strength among single-household elderly in Korea: data from 2014 and 2019 Korea National Health and Nutrition Examination Survey (KNHANES).Physical activity and nutrition · 2024Article
- Influence of frailty status on the health-related quality of life in older patients with chronic low back pain: a retrospective observational study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Observational
- Chronic pain in older adults with disabilities is associated with fall-related injuries: a prospective cohort study.European geriatric medicine · 2024Article
- Effects of Exercise on Frailty in Older People Based on ACSM Recommendations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of clinical medicine · 2024Review
- A Narrative Review of the Utilisation of the SHARE Frailty Instruments (SHARE-FI and SHARE-FI75+) in the Literature.Journal of frailty, sarcopenia and falls · 2023Review
- The role of the microcirculation and integrative cardiovascular physiology in the pathogenesis of ICU-acquired weakness.Frontiers in physiology · 2023Review
- Implications of frailty interventions from Korean frailty and aging cohort study.Aging medicine (Milton (N.S.W)) · 2021Article
- The Effects and Mechanisms of Exercise on the Treatment of Depression.Frontiers in psychiatry · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExercise has shown being effective for managing chronic pain and preventing frailty status in older adults but the effect of an exercise program in the quality of life of pre-frail older adults with chronic pain remains unclear. Our objective was to evaluate the effectiveness of multicomponent structured physical exercise program for pre-frail adults aged 65 years or more with chronic pain to improve their perceived health related quality of life, compared with usual care.
methodsOpen label randomized controlled trial. Participants were community-dwelling pre-frail older adults aged 65 years or older with chronic pain and non-dependent for basic activities of daily living attending a Primary Healthcare Centre. Forty-four participants were randomly allocated to a control group (n = 20) that received usual care or an intervention group (n = 24) that received an 8-week physical activity and education program. Frailty status (SHARE Frailty Index), quality of life (EuroQol-5D-5L), pain intensity (Visual Analogue Scale), physical performance (Short Physical Performance Battery) and depression (Yessavage) were assessed at baseline, after the intervention and after 3 months follow-up. The effect of the intervention was analysed by mean differences between the intervention and control groups.
resultsThe follow-up period (3 months) was completed by 32 patients (73%), 17 in the control group and 15 in the intervention group. Most participants were women (78.1%) with a mean age (standard deviation) of 77.2 (5.9) years and a mean pain intensity of 48.1 (24.4) mm. No relevant differences were found between groups at baseline. After the intervention, mean differences in the EuroQol Index Value between control and intervention groups were significant (- 0.19 95% CI(- 0.33- -0.04)) and remained after 3 months follow-up (- 0.21 95% CI(- 0.37- -0.05)). Participants in the exercise group showed better results in pain intensity and frailty after the intervention, and an improvement in physical performance after the intervention and after 3 months.
conclusionsAn eight-week physical activity and education program for pre-frail older adults with chronic pain, compared with usual care, could be effective to improve quality of life after the intervention and after three-months follow-up. STUDY REGISTRATION DETAILS: This study was retrospectively registered in ClinicalTrials.gov with the identifier NCT04045535 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.