Evidence map›Paper›PMID 33031819›Full record

ReviewClinical biochemistry2020

Canadian society of clinical chemists (CSCC) interim consensus guidance for testing and reporting of SARS-CoV-2 serology.

Dana Bailey, Danijela Konforte, Vilte E Barakauskas, Paul M Yip, Vathany Kulasingam, Mohamed Abou El Hassan, Lori A Beach, Ivan M Blasutig, Peter Catomeris, Kent C Dooley and 7 more

Abstract readReviewConsensus Statement
In one paragraph

Review in Clinical biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Dana BaileyDynacare, Brampton, Canada. Electronic address: baileyd@dynacare.ca.
Danijela KonforteLifeLabs, Toronto, Canada. Electronic address: danijela.konforte@lifelabs.com.
Vilte E BarakauskasDepartment of Pathology and Laboratory Medicine, BC Children's and Women's Hospital, Vancouver, Canada. Electronic address: vilte.barakauskas@cw.bc.ca.
Paul M YipDepartment of Laboratory Medicine and Molecular Diagnostics, Sunnybrook Health Sciences Centre, Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. Electronic address: paul.yip@utoronto.ca.
Vathany KulasingamDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Department of Clinical Biochemistry, University Health Network, Toronto, Canada. Electronic address: vathany.kulasingam@uhn.ca.
Mohamed Abou El HassanLifeLabs, Toronto, Canada; Department of Pathology, Dalhousie University, Halifax, Canada. Electronic address: Mohamed.Abouelhassan@lifelabs.com.
Lori A BeachDepartment of Pathology, Dalhousie University, Halifax, Canada; Pathology and Laboratory Medicine, IWK Health Centre, Halifax, Canada. Electronic address: lori.beach@iwk.nshealth.ca.
Ivan M BlasutigEastern Ontario Regional Laboratory Association, Canada; CHEO, Ottawa, Canada; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada. Electronic address: iblasutig@cheo.on.ca.
Peter CatomerisDynacare, Brampton, Canada. Electronic address: catomerisp@dynacare.ca.
Kent C DooleyLaboratory Medicine and Pathology, University of British Columbia, Vancouver, Canada; LifeLabs, Vancouver, Canada. Electronic address: kent.dooley@lifelabs.com.
Yanping GongPathology & Molecular Medicine, Queen's University, Kingston, Canada. Electronic address: Yanping.Gong@kingstonhsc.ca.
Peter KavsakDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada. Electronic address: kavsakp@mcmaster.ca.
Edward W RandellDepartment of Laboratory Medicine, Faculty of Medicine, Memorial University of Newfoundland, Newfoundland, Canada. Electronic address: ed.randell@easternhealth.ca.
Jason L RobinsonHealth PEI, Charlottetown, Canada. Electronic address: jlrobinson@ihis.org.
Julie ShawEastern Ontario Regional Laboratory Association, Canada; Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada. Electronic address: julshaw@eorla.ca.
Jennifer TaherDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Pathology & Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada. Electronic address: jennifer.taher@sinaihealth.ca.
Nicole White-Al HabeebLifeLabs, Toronto, Canada. Electronic address: nicole.white-alhabeeb@lifelabs.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical laboratories across the world are working to validate and perform testing for SARS-CoV-2 antibodies. Herein, we present interim consensus guidance for Canadian clinical laboratories testing and reporting SARS-CoV-2 serology, with emphasis on the capabilities and limitations of these tests and recommendations for interpretative comments in an effort to achieve harmonized laboratory practices. The consensus document provides a broad overview of topics including sample type and contamination risk; kinetics of antibody response to COVID-19 and the impact on serology testing; clinical utility of SARS-CoV-2 serology testing; clinical performance of commercial laboratory-based assays commonly deployed in North America; recommendations for interim reporting; utility of SARS-CoV-2 antibody testing for pediatric patients; and utility of point-of-care testing. The information is based on the current literature and is subject to change as additional information becomes available.

Indexed as

Chemistry, PharmaceuticalCOVID-19COVID-19 Serological TestingPandemicsSARS-CoV-2Societies, MedicalCanadaHumansAntibodyClinical performanceCOVID-19Guidance documentSARS-CoV-2Serology

Identifiers

PMID33031819
PMCPMC7536550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.