ArticleJournal of veterinary internal medicine2020
Prevalence and risk factors for atrial fibrillation in dogs with myxomatous mitral valve disease.
Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Pre-anaesthetic risk assessment and management of dogs with myxomatous mitral valve disease: a spectrum of care narrative review.The Journal of small animal practice · 2026Review
- Outcomes of mitral valve repair in dogs with myxomatous mitral valve disease and preoperative atrial fibrillation.Journal of veterinary internal medicine · 2026Article
- Clinical findings and risk factors for clinical outcomes in dogs with myxomatous mitral valve disease hospitalized for cardiogenic pulmonary edema.Frontiers in veterinary science · 2026Article
- Signalment, clinical characteristics, and echocardiographic findings in dogs affected by secondary atrial fibrillation with and without concomitant frequent and complex ventricular arrhythmias.Frontiers in veterinary science · 2026Article
- Ability of Surface Electrocardiography in Predicting Ventricular Arrhythmias in Dogs with Secondary Atrial Fibrillation.Animals : an open access journal from MDPI · 2025Article
- Arrhythmias across the tree of life: comparative insights for human electrophysiology.Frontiers in cardiovascular medicine · 2025Review
- Evaluation of Galectin-3 in Dogs with Atrial Fibrillation.Animals : an open access journal from MDPI · 2024Article
- Risk Factors for Atrial Fibrillation in the Dog: A Systematic Review.Veterinary sciences · 2024Review
- Article
- A Retrospective Cohort Evaluation of Left Ventricular Remodeling, Perioperative Complications and Outcome in Medium and Large Size Dogs with Patent Ductus Arteriosus after Percutaneous Closure.Veterinary sciences · 2023Article
- Two cases of new-born puppies with transient pulmonary edema.Veterinary research forum : an international quarterly journal · 2023Article
- Prevalence and prognostic role of L wave and selected clinical and echocardiographic variables in dogs with atrial fibrillation.Journal of veterinary internal medicine · 2023Article
- Risk factors for atrial fibrillation in dogs with dilated cardiomyopathy.Frontiers in veterinary science · 2023Article
- Combination of the Modified Loop Technique and De Vega Annuloplasty in Dogs with Mitral Regurgitation.Animals : an open access journal from MDPI · 2022Article
- Prevalence of sudden cardiac death in dogs with atrial fibrillation.Journal of veterinary internal medicine · 2021Article
- Red Cell Distribution Width Has a Negative Prognostic Role in Dogs with Myxomatous Mitral Valve Disease.Animals : an open access journal from MDPI · 2021Article
- Prevalence and risk factors for atrial fibrillation in dogs with myxomatous mitral valve disease.Journal of veterinary internal medicine · 2020Article
- Serum digoxin concentrations in dogs with atrial fibrillation under long term digoxin treatment.Open veterinary journalArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtrial fibrillation (AF) is a common supraventricular arrhythmia more frequently observed in large breed dogs.
objectivesEstimate the prevalence of AF in dogs with myxomatous mitral valve disease (MMVD) and identify risk factors for developing AF. ANIMALS: A total of 2194 client-owned dogs with MMVD, including 1280, 588, 290, and 36 dogs in ACVIM stages B1, B2, C, and D, respectively.
methodsRetrospective, cross-sectional study. The medical databases of 3 veterinary teaching hospitals were reviewed. Inclusion criteria were a diagnosis of MMVD after complete cardiovascular evaluation and cardiac rhythm assessment using routine 2-minute ECG or good quality ECG tracing during echocardiographic examination.
resultsAtrial fibrillation was diagnosed in 59 dogs with a prevalence of 2.7%. Univariate analysis showed that mixed breed, male sex, advanced ACVIM stage, left atrial and ventricular enlargement, fractional shortening (FS), and presence of pulmonary hypertension were significantly associated with development of AF. According to 2 multivariable models, the left atrium (LA)-to-aorta ratio (odds ratio [OR] = 14.011, 7.463-26.304), early trans-mitral velocity (OR = 2.204, 1.192-4.076), body weight (OR = 1.094, 1.058-1.130), and FS (OR = 0.899, 0.865-0.934) and LA (OR = 5.28, 3.377-8.092), advanced ACVIM stage (OR = 4.922, 1.481-16.353), and FS (OR = 0.919, 0.881-0.959) were significant predictors of AF for models 1 and 2, respectively. CONCLUSIONS AND CLINICAL IMPORTANCE: Atrial fibrillation is an uncommon complication of MMVD and is significantly associated with the more advanced stage of the disease, increased LA dimension and body weight, and decreased FS.
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