Evidence map›Paper›PMID 33031565›Full record

ArticleAllergy2021

Assessing the protective role of allergic disease in gastrointestinal tract cancers using Mendelian randomization analysis.

Shuai Yuan, Mathew Vithayathil, Siddhartha Kar, Paul Carter, Amy M Mason, Shao-Hua Xie, Stephen Burgess, Susanna C Larsson

Open access · hybridAbstract readLetter
In one paragraph

Article in Allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Association of Genetic Liability to Allergic Diseases with Overall and Early-Onset Colorectal Cancer Risk: A Mendelian Randomization Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Shuai YuanUnit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-5055-5627
Mathew VithayathilMRC Cancer Unit, University of Cambridge, Cambridge, UK.
Siddhartha KarMRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK.
Paul CarterDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Amy M MasonBritish Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Shao-Hua XieUpper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Stephen BurgessDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Susanna C LarssonUnit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-0118-0341
University of Cambridge · GBKarolinska Institutet · SEKarolinska University Hospital · SEUniversity of Bristol · GBUppsala University · SE

Funding

Cancer Research UK 19169Medical Research Council MC_UU_00002/7Wellcome Trust 204623/Z/16/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal NeoplasmsHypersensitivityGenetic Predisposition to DiseaseHumansMendelian Randomization AnalysisPolymorphism, Single Nucleotide

Identifiers

PMID33031565
PMCPMC8411419
OpenAlexW3092431535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.