Evidence map›Paper›PMID 33031277›Full record

ArticleMedicine2020

Efficacy and safety of traditional Chinese herbal formula combined with western medicine for gastroesophageal reflux disease: A protocol for systematic review and meta-analysis.

Wuhong Lin, Guihua Huang, Xirong Liu, Huasheng Lin, Heng Zhou, Chunbing Feng, Tingshuai Wang, Renjiu Liang

Abstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wuhong LinThe School of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province.ORCID 0000-0003-3073-0779
Guihua HuangDepartment of Spleen, Stomach, and Liver Disease, The First Affiliated Hospital of Guangxi University of Chinese Medicine.
Xirong LiuDepartment of Spleen, Stomach, and Liver Disease, The First Affiliated Hospital of Guangxi University of Chinese Medicine.
Huasheng LinDepartment of Spleen, Stomach, and Liver Disease, The First Affiliated Hospital of Guangxi University of Chinese Medicine.
Heng ZhouDepartment of Spleen, Stomach, and Liver Disease, The First Affiliated Hospital of Guangxi University of Chinese Medicine.
Chunbing FengEmergency Department of Yulin Hospital of Traditional Chinese Medicine.
Tingshuai WangThe School of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province.
Renjiu LiangGraduate School, Guangxi University of Chinese Medicine, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe combined therapy of Chinese herbal formula and western medicine against gastroesophageal reflux disease (GERD) could significantly improve the clinical effect, reduce the recurrence rate and the side effects of western medicine, and even reduce the dosage and course of treatment of western medicine. This study tried to systematically evaluate the efficacy and safety traditional Chinese herbal formula combined with western medicine in the treatment of GERD.

methodsRandomized controlled trials of traditional Chinese herbal formula combined with western medicine for GERD patients will be systematically searched using the PubMed, Embase, Medline, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang database, Chongqing VIP Chinese Science and Technology Periodical Database, and Chinese Biological and Medical database (CMB) until Aug. 28, 2020. Two researchers will perform data extraction and risk of bias assessment independently. Statistical analysis will be conducted in RevMan 5.3.

resultsThis study will summarize the present evidence by exploring the efficacy and safety of traditional Chinese herbal formula combined with western medicine in the treatment of GERD.

conclusionsThe findings of the study will help to determine potential benefits of traditional Chinese herbal formula combined with western medicine against GERD. ETHICS AND DISSEMINATION: The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. OSF REGISTRATION NUMBER: DOI 10.17605/OSF.IO/RSAVF.

Indexed as

AntacidsDrugs, Chinese HerbalDrug Therapy, CombinationGastroesophageal RefluxHistamine H2 AntagonistsHumansMeta-Analysis as TopicProton Pump InhibitorsRandomized Controlled Trials as TopicResearch DesignSystematic Reviews as TopicAntacidsDrugs, Chinese HerbalHistamine H2 AntagonistsProton Pump Inhibitors

Identifiers

PMID33031277
PMCPMC7544302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.