Observational studyCritical care medicine2020
Association Between Pediatric Delirium and Quality of Life After Discharge.
Observational study in Critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Prevalence of pediatric delirium among critically ill children: a meta-analysis of observational studies.Frontiers in pediatrics · 2026Pooled it
- Impact of Delirium on Pediatric Critical Care Outcomes and Management Strategies: A Systematic Review and Meta-Analysis.Journal of nursing management · 2026Pooled it
- Antipsychotic Medications for Delirium Treatment in the Pediatric Intensive Care Unit: A Systematic Review.Paediatric drugs · 2025Pooled it
- Neurocognitive functioning and health-related quality of life of children after pediatric intensive care admission: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Pooled it
- Delirium in Children Hospitalized with Acute COVID-19 or MIS-C: Secondary Analysis of the 2020-2021 Global Consortium Study of Neurologic Dysfunction in COVID-19.Neurocritical care · 2026Observational
- The Lived Experience of Delirium in a Critically Ill Child: A Narrative Study.Scandinavian journal of caring sciences · 2026Article
- Risk of Neuropsychiatric Disorders After Pediatric Delirium in Children Under 12: A Cohort Study.Psychiatry investigation · 2026Article
- PICU associated social-emotional adversity in early childhood cancer patients: consequences in neurodevelopment and mental health.Frontiers in oncology · 2026Review
- Impact of meningoencephalitis and sepsis on delirium and subsequent neurological impairment in pediatric patients: a prospective proof-of-concept biomarker and EEG study.Scientific reports · 2025Article
- Sleep fragmentation in critically ill children: a review of contributing factors in the pediatric intensive care unit and neurodevelopmental outcomes.Frontiers in sleep · 2025Review
- Delirium in neonates and infants: a scoping review protocol.BMJ open · 2024Article
- Adapting the Cornell assessment of pediatric delirium for Swedish context: translation, cultural validation and inter-rater reliability.BMC pediatrics · 2024Article
- Severe Pediatric Neurological Manifestations With SARS-CoV-2 or MIS-C Hospitalization and New Morbidity.JAMA network open · 2024Article
- Two months outcomes following delirium in the pediatric intensive care unit.European journal of pediatrics · 2024Article
- Risk Factors and Nomogram Model of Postoperative Delirium in Children with Congenital Heart Disease: A Single-Center Prospective Study.Pediatric cardiology · 2024Article
- Challenges of the Implementation of a Delirium Rate Scale in a Pediatric Intensive Care Unit: A Qualitative Approach.Healthcare (Basel, Switzerland) · 2023Article
- Incidence, associated factors, and outcomes of delirium in critically ill children in china: a prospective cohort study.BMC psychiatry · 2023Observational
- Pediatric Delirium Educational Tool Development With Intensive Care Unit Clinicians and Caregivers in Canada: Focus Group Study.JMIR pediatrics and parenting · 2023Article
- The occurrence of delirium diagnosis among youth hospitalizations in the United States: A Kids' Inpatient Database analysis.Acta psychiatrica Scandinavica · 2023Article
- Delirium in Pediatric Patients With Respiratory Insufficiency Requiring Noninvasive Ventilation.Journal of clinical medicine research · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
Abstract
objectiveDelirium occurs frequently in critically ill children, with highest rates reported in children under 5 years old. The objective of this study was to measure the residual effect of delirium on quality of life at 1 and 3 months after hospital discharge.
designProspective observational cohort study.
settingUrban academic PICU. PATIENTS: Children younger than five years of age at time of admission to the PICU.
interventionsAll children were screened for delirium (using the Cornell Assessment for Pediatric Delirium) throughout their stay in the PICU. Quality of life was measured using the Infant-Toddler Quality of Life questionnaire at three time points: baseline, 1 month, and 3 months after hospital discharge. Infant-Toddler Quality of Life scores were compared between children who did and did not develop delirium. MEASUREMENTS AND MAIN
resultsTwo hundred seven children were enrolled. One hundred twenty-two completed the 1-month follow-up, and 117 completed the 3-month follow-up. Fifty-six children (27%) developed delirium during their PICU stay. At follow-up, Infant-Toddler Quality of Life scores for the PICU cohort overall were consistently lower than age-related norms. When analyzed by delirium status, children who had experienced delirium scored lower in every quality of life domain when compared with children who did not experience delirium. Even after controlling for severity of illness, delirious patients demonstrated an average 11-point lower general health score than nondelirious patients (p = 0.029).
conclusionThis pilot study shows an independent association between delirium and decreased quality of life after hospital discharge in young children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.