ArticleAmerican journal of respiratory and critical care medicine2021
Inflammation and Coagulation during Critical Illness and Long-Term Cognitive Impairment and Disability.
Open access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Mechanisms underlying neurocognitive dysfunction following critical illness: a systematic review.Anaesthesia · 2025Pooled it
- Persistent immune, coagulation and cardiac dysregulation are correlated with later post-discharge mortality in children with severe malnutrition.BMC medicine · 2026Trial
- Lung endothelial cytopathic tau is sufficient to impair long-term potentiation during infection.American journal of respiratory cell and molecular biology · 2026Article
- Inflammatory Biomarkers and Post-Intensive Care Syndrome: A Prospective Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- C-reactive protein-triglyceride glucose index and its dynamic trajectories on all-cause mortality in critically ill children: a longitudinal, retrospective cohort study.Pediatric research · 2026Article
- Neuroimmune Mechanisms Transforming Acute Injury to Long-Term Brain Dysfunction After Sepsis.Clinics in chest medicine · 2026Review
- Inflammatory indices as independent predictors of in-hospital mortality in acute upper gastrointestinal bleeding.BMC gastroenterology · 2026Observational
- Post-Intensive Care Syndrome: From Diagnosis To Treatment.Deutsches Arzteblatt international · 2026Review
- Post-intensive Care Syndrome (PICS): an American Association for the Surgery of Trauma Critical Care Committee Consensus Guideline - Defining, Recognizing, and Managing PICS Associated Physical Impairment, Cognitive Dysfunction, and Thromboinflammatory Dysregulation.Trauma surgery & acute care open · 2026Article
- Machine learning-based transcriptomic analysis identifies candidate genes in sepsis-induced coagulopathy and explores the immunomodulatory potential of baicalein.Human genomics · 2025Article
- Health-related quality of life, physical and mental capacity at one year follow up of COVID-19 ICU patients: A prospective cohort study.Journal of patient-reported outcomes · 2025Article
- Sleep promotion in the hospitalized elderly.Sleep · 2025Article
- Observational
- Management of severe acute encephalopathy in the ICU: an expert consensus statement from the french society of intensive care medicine.Annals of intensive care · 2025Review
- Altered cognition in patients following pulmonary embolism.Frontiers in medicine · 2025Article
- Systemic inflammation and delirium during critical illness.Intensive care medicine · 2024Article
- Associations between static and dynamic changes of platelet counts and in-hospital mortality in critical patients with acute heart failure.Scientific reports · 2024Article
- Lung endothelium, tau, and amyloids in health and disease.Physiological reviews · 2024Review
- A Set of Possible Markers for Monitoring Heart Failure and Cognitive Impairment Associated: A Review of Literature from the Past 5 Years.Biomolecules · 2024Review
- Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Nathan E BrummelDivision of Pulmonary, Critical Care, and Sleep Medicine and.ORCID 0000-0003-4308-0015
Christopher G HughesCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
Jennifer L ThompsonCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
James C JacksonCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
Pratik PandharipandeCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
J Brennan McNeilCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
Rameela RamanCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
Onur M OrunCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
Lorraine B WareCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
Gordon R BernardCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
E Wesley ElyCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.
Timothy D GirardCritical Illness, Brain Dysfunction, and Survivorship Center, Nashville, Tennessee.ORCID 0000-0002-9833-4871
Pulmonary and Allergy Associates · USVanderbilt University · USThe Ohio State University Wexner Medical Center · USUniversity of Pittsburgh · USVA Tennessee Valley Healthcare System · US
Funding
The MIND USA StudyR01AG035117 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ELY, E WESLEY · 2011 to 2016
$7.3MAltering Sedation Paradigms to Improve Brain Injury and Survival in Severe SepsisR01HL111111 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PANDHARIPANDE, PRATIK · 2012 to 2017
$3.7MThe MIND ICU StudyR01AG027472 · NIA · VANDERBILT UNIVERSITY · PI ELY, E WESLEY · 2006 to 2010
$3.0MMitochondrial Determinants of Cognitive Outcomes in ARDS and Sepsis - SupplementR01HL135144 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GIRARD, TIMOTHY D · 2017 to 2021
$2.2MMidcareer Investigator Award in Patient-Oriented Research in Acute Lung InjuryK24HL103836 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WARE, LORRAINE B · 2010 to 2020
$1.6MLong Term Outcomes of Physical Activity in Older Adults with Critical IllnessK76AG054864 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BRUMMEL, NATHAN E · 2016 to 2020
$826kPredictors of Cognitive Impairment in Survivors of Critical IllnessK23AG034257 · NIA · VANDERBILT UNIVERSITY · PI GIRARD, TIMOTHY D · 2009 to 2013
$684kNHLBI NIH HHS K24 HL103836NHLBI NIH HHS R01 HL111111NHLBI NIH HHS R01 HL135144NIA NIH HHS K23 AG034257NIA NIH HHS K76 AG054864NIA NIH HHS R01 AG027472NIA NIH HHS R01 AG035117
Abstract
PubMed holds no abstract for this paper.
Indexed as
AgedBiomarkersBlood Coagulation DisordersCognitive DysfunctionC-Reactive ProteinCritical IllnessFemaleHumansInflammationInterferon Regulatory FactorsMaleMatrix MetalloproteinasesMiddle AgedPersons with DisabilitiesPredictive Value of TestsProspective StudiesBiomarkersC-Reactive ProteinInterferon Regulatory FactorsMatrix MetalloproteinasesTumor Necrosis Factorscoagulationcritical illnessdementiadisabilityinflammation
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.