Evidence map›Paper›PMID 33030824›Full record

ReviewBiomedica : revista del Instituto Nacional de Salud2020

Congenital Langerhans cell histiocytosis

Katherine Barrios, Oscar Patiño, Nelson Muñoz, Carlos Moneriz

Abstract readCase ReportsReview
In one paragraph

Review in Biomedica : revista del Instituto Nacional de Salud, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katherine BarriosGrupo de Investigación de Bioquímica y Enfermedad, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia; Hospital Infantil Napoleón Franco Pareja, Cartagena, Colombia. kbarriosr19@gmail.com.
Oscar PatiñoGrupo de Investigación de Bioquímica y Enfermedad, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia. oscar.patino.26@gmail.com.
Nelson MuñozGrupo de Investigación de Bioquímica y Enfermedad, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia; Hospital Infantil Napoleón Franco Pareja, Cartagena, Colombia; Departamento de Pediatría, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia . crisca53@gmail.com.
Carlos MonerizGrupo de Investigación de Bioquímica y Enfermedad, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia. cmonerizp@unicartagena.edu.co.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Langerhans cell histiocytosis is a rare pathology with different clinical manifestations in the neonatal period ranging from isolated bone lesions to systemic compromise. We report a case of Langerhans cell histiocytosis including a literature review focused on the clinical manifestations, diagnosis, and treatment. A one-month-old patient was brought to medical consultation with lymphadenopathy and skin lesions, which were initially managed as an infectious pathology. The disease continued its progression without improvement with the treatment until the patient died due to respiratory failure. The lymph node and skin biopsies revealed infiltration of atypical cells with positive immunohistochemistry for S100, CD1, and CD68 confirming Langerhans cell histiocytosis. This disorder represents a great challenge and, therefore, it is important to alert and sensitize medical teams about it for timely diagnosis and management.

Indexed as

BiopsyCytomegalovirus InfectionsDiagnosis, DifferentialDisease ProgressionFatal OutcomeHistiocytosis, Langerhans-CellHumansInfantLymphadenopathyMaleSkinSkin DiseasesSkin Diseases, ViralColombiahistiocytosisinfantLangerhans cellsnewborn

Identifiers

PMID33030824
PMCPMC7666860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.