Evidence map›Paper›PMID 33030802›Full record

ArticleEMBO reports2020

Prominin-1-Radixin axis controls hepatic gluconeogenesis by regulating PKA activity.

Hyun Lee, Dong-Min Yu, Jun Sub Park, Hwayeon Lee, Jun-Seok Kim, Hong Lim Kim, Seung-Hoi Koo, Jae-Seon Lee, Sungsoo Lee, Young-Gyu Ko

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EMBO reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hyun Lee *Tunneling Nanotube Research Center, Korea University, Seoul, Korea.
Dong-Min Yu *Tunneling Nanotube Research Center, Korea University, Seoul, Korea.
Jun Sub ParkTunneling Nanotube Research Center, Korea University, Seoul, Korea.
Hwayeon LeeTunneling Nanotube Research Center, Korea University, Seoul, Korea.
Jun-Seok KimTunneling Nanotube Research Center, Korea University, Seoul, Korea.
Hong Lim KimLaboratory of Electron Microscope, Integrative Research Support Center, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Seung-Hoi KooTunneling Nanotube Research Center, Korea University, Seoul, Korea.
Jae-Seon LeeDepartment of Molecular Medicine, Inha University College of Medicine, Incheon, Korea.
Sungsoo LeeTunneling Nanotube Research Center, Korea University, Seoul, Korea.ORCID 0000-0002-8192-0946
Young-Gyu KoTunneling Nanotube Research Center, Korea University, Seoul, Korea.ORCID 0000-0002-0969-2598
Korea University · KRCatholic University of Korea · KRInha University · KR

Funding

Korea UniversityNational Research Foundation of Korea 2015R1A5A1009024National Research Foundation of Korea 2017R1A6A3A01009334National Research Foundation of Korea 2017R1D1A1A02017979
6 · The paper itself

Abstract

Prominin-1 (Prom1) is a major cell surface marker of cancer stem cells, but its physiological functions in the liver have not been elucidated. We analyzed the levels of mRNA transcripts in serum-starved primary WT (Prom1

Indexed as

GluconeogenesisGlucoseAC133 AntigenAnimalsCytoskeletal ProteinsHepatocytesLiverMembrane ProteinsMiceAC133 AntigenCytoskeletal ProteinsGlucoseMembrane ProteinsProm1 protein, mouseradixincAMP signalinggluconeogenesisProminin-1protein kinase Aradixin

Identifiers

PMID33030802
PMCPMC7645247
OpenAlexW3091954122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.