ArticleHuman brain mapping2021
Prediction of 7-year's conversion from subjective cognitive decline to mild cognitive impairment.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Grey matter changes on brain MRI in subjective cognitive decline: a systematic review.Alzheimer's research & therapy · 2022Pooled it
- Development and Validation of a Predictive Model for Identification of Cognitive Impairment Risk in Older Adults with Subjective Cognitive Decline：A Longitudinal Study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Do Perspectives Matter? Comparing Patient, Informant, and Clinician Subjective Cognitive Decline.medRxiv : the preprint server for health sciences · 2026Article
- Predicting the progression of MCI and Alzheimer's disease on structural brain integrity and other features with machine learning.GeroScience · 2026Article
- Individualized prediction of transition from subjective cognitive decline to mild cognitive impairment based on multimodal MRI: a 10-year follow-up study.The journal of prevention of Alzheimer's disease · 2026Article
- Article
- Memory Gate Controlled by Contexts: Potential Key Structure That Could Link Small Associative Failures With Severe Cognitive Disorders.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- Supraspan memory performance is impaired in subjective cognitive impairment compared to cognitively unimpaired individuals.Scientific reports · 2025Article
- Hybrid multi-modality multi-task learning for forecasting progression trajectories in subjective cognitive decline.Neural networks : the official journal of the International Neural Network Society · 2025Article
- Estimating Chronological Age From the Electrical Activity of the Brain: How EEG-Age Can Be Used as a Marker of General Brain Functioning.Psychophysiology · 2025Article
- Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns.Alzheimer's research & therapy · 2024Article
- Predictive Models for the Transition from Mild Neurocognitive Disorder to Major Neurocognitive Disorder: Insights from Clinical, Demographic, and Neuropsychological Data.Biomedicines · 2024Article
- Does the Cognitive Change Index Predict Future Cognitive and Clinical Decline? Longitudinal Analysis in a Demographically Diverse Cohort.Journal of Alzheimer's disease : JAD · 2024Article
- The neurocognitive disorder cohort RIFADE: Aims, methods, first results showing cognitive improvement in a subgroup.European archives of psychiatry and clinical neuroscience · 2023Article
- Attention-Guided Autoencoder for Automated Progression Prediction of Subjective Cognitive Decline With Structural MRI.IEEE journal of biomedical and health informatics · 2023Article
- Eliciting brain waves of people with cognitive impairment during meditation exercises using portable electroencephalography in a smart-home environment: a pilot study.Frontiers in aging neuroscience · 2023Article
- A Machine Learning Classifier for Predicting Stable MCI Patients Using Gene Biomarkers.International journal of environmental research and public health · 2022Article
- Assessing clinical progression from subjective cognitive decline to mild cognitive impairment with incomplete multi-modal neuroimages.Medical image analysis · 2022Article
- Subjective cognitive decline is associated with a higher risk of objective cognitive decline: A cross-sectional and longitudinal study.Frontiers in psychiatry · 2022Article
- Subjective Cognitive Decline: Is a Resilient Personality Protective Against Progression to Objective Cognitive Impairment? Findings from Two Community-Based Cohort Studies.Journal of Alzheimer's disease : JAD · 2022Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subjective cognitive decline (SCD) is a high-risk yet less understood status before developing Alzheimer's disease (AD). This work included 76 SCD individuals with two (baseline and 7 years later) neuropsychological evaluations and a baseline T1-weighted structural MRI. A machine learning-based model was trained based on 198 baseline neuroimaging (morphometric) features and a battery of 25 clinical measurements to discriminate 24 progressive SCDs who converted to mild cognitive impairment (MCI) at follow-up from 52 stable SCDs. The SCD progression was satisfactorily predicted with the combined features. A history of stroke, a low education level, a low baseline MoCA score, a shrunk left amygdala, and enlarged white matter at the banks of the right superior temporal sulcus were found to favor the progression. This is to date the largest retrospective study of SCD-to-MCI conversion with the longest follow-up, suggesting predictable far-future cognitive decline for the risky populations with baseline measures only. These findings provide valuable knowledge to the future neuropathological studies of AD in its prodromal phase.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.