Evidence map›Paper›PMID 33030603›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021

Brain stiffness following recovery in a patient with an episode of low-pressure hydrocephalus: case report.

William C Olivero, Arundhati Biswas, Tracey M Wszalek, Bradley P Sutton, Curtis L Johnson

Abstract readCase Reports
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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Pediatric low-pressure hydrocephalus: a case series and re-analysis of a rare disease.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  2. Review
  3. Commentary on the article "Brain stiffness following recovery in a patient with an episode of low-pressure hydrocephalus: case report".Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

William C OliveroCarle Neuroscience Institute, Carle Foundation Hospital, Urbana, IL, USA. olib@illinois.edu.
Arundhati BiswasCarle Neuroscience Institute, Carle Foundation Hospital, Urbana, IL, USA.
Tracey M WszalekBeckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Bradley P SuttonBeckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Curtis L JohnsonDepartment of Biomedical Engineering, University of Delaware, Newark, DE, USA. clj@udel.edu.ORCID 0000-0002-7760-131X
Carle Foundation Hospital · USUniversity of Illinois Urbana-Champaign · USUniversity of Delaware · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors describe a follow-up to a case of a 19-year-old female with shunted aqueductal stenosis who presented with low-pressure hydrocephalus during a shunt malfunction. Shortly after management with CSF drainage at negative pressure, a magnetic resonance elastography scan was performed and revealed very low brain stiffness (high compliance). Here we present the case of the same patient seen 2 years later, now 21 years old, who again received a magnetic resonance elastography scan after receiving treatment for another shunt malfunction, this time with high intracranial pressure. This scan revealed recovery of brain stiffness to a near normal value for the patients' age. This observation suggests the low brain stiffness observed during the low-pressure hydrocephalus event is reversible. The authors discuss these findings in relation to biomechanical hypotheses of low-pressure hydrocephalus.

Indexed as

HydrocephalusHydrocephalus, Normal PressureAdultBrainCerebral AqueductCerebrospinal Fluid ShuntsDrainageFemaleHumansIntracranial PressureYoung AdultComplianceElastographyLow-pressure hydrocephalusStiffness

Identifiers

PMID33030603
OpenAlexW3091915067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.