Evidence map›Paper›PMID 33030429›Full record

ArticleeLife2020

PLK-1 promotes the merger of the parental genome into a single nucleus by triggering lamina disassembly.

Griselda Velez-Aguilera, Sylvia Nkombo Nkoula, Batool Ossareh-Nazari, Jana Link, Dimitra Paouneskou, Lucie Van Hove, Nicolas Joly, Nicolas Tavernier, Jean-Marc Verbavatz, Verena Jantsch and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  9. Polo-like kinase 1 prevents excess microtubule polymerization inbioRxiv : the preprint server for biology · 2024
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  17. Post-Translational Modification of Lamins: Mechanisms and Functions.Frontiers in cell and developmental biology · 2022
    Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Griselda Velez-AguileraProgramme Equipe Labéllisée Ligue Contre le Cancer - Team Cell Cycle & Development - Université de Paris, CNRS, Institut Jacques Monod, Paris, France.ORCID 0000-0002-9662-8833
Sylvia Nkombo NkoulaProgramme Equipe Labéllisée Ligue Contre le Cancer - Team Cell Cycle & Development - Université de Paris, CNRS, Institut Jacques Monod, Paris, France.
Batool Ossareh-NazariProgramme Equipe Labéllisée Ligue Contre le Cancer - Team Cell Cycle & Development - Université de Paris, CNRS, Institut Jacques Monod, Paris, France.
Jana LinkDepartment of Chromosome Biology, Max Perutz Laboratories, University of Vienna, Vienna Biocenter, Vienna, Austria.
Dimitra PaouneskouDepartment of Chromosome Biology, Max Perutz Laboratories, University of Vienna, Vienna Biocenter, Vienna, Austria.
Lucie Van HoveProgramme Equipe Labéllisée Ligue Contre le Cancer - Team Cell Cycle & Development - Université de Paris, CNRS, Institut Jacques Monod, Paris, France.
Nicolas JolyProgramme Equipe Labéllisée Ligue Contre le Cancer - Team Cell Cycle & Development - Université de Paris, CNRS, Institut Jacques Monod, Paris, France.
Nicolas TavernierProgramme Equipe Labéllisée Ligue Contre le Cancer - Team Cell Cycle & Development - Université de Paris, CNRS, Institut Jacques Monod, Paris, France.
Jean-Marc VerbavatzUniversité de Paris, CNRS, Institut Jacques Monod, Paris, France.
Verena JantschDepartment of Chromosome Biology, Max Perutz Laboratories, University of Vienna, Vienna Biocenter, Vienna, Austria.ORCID 0000-0002-1978-682X
Lionel PintardProgramme Equipe Labéllisée Ligue Contre le Cancer - Team Cell Cycle & Development - Université de Paris, CNRS, Institut Jacques Monod, Paris, France.ORCID 0000-0003-0286-4630
Centre National de la Recherche Scientifique · FRUniversity of Vienna · AT

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Agence Nationale de la Recherche ANR-11-LABX-0071Agence Nationale de la Recherche ANR-17-CE13-0011Austrian Science Fund P32903-BConsejo Nacional de Ciencia y Tecnología CVU364106NIH HHS P40 OD010440
6 · The paper itself

Abstract

Life of sexually reproducing organisms starts with the fusion of the haploid egg and sperm gametes to form the genome of a new diploid organism. Using the newly fertilized

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsEmbryo, NonmammalianGenome, HelminthLamininMitosisPhosphorylationPolo-Like Kinase 1Protein Serine-Threonine KinasesCaenorhabditis elegans ProteinsLamininLMN-1 protein, C elegansplk-1 protein, C elegansPolo-Like Kinase 1Protein Serine-Threonine KinasesC. eleganscell biologycell cycledevelopmentlaminmitosispolo-like kinase 1zygote

Identifiers

PMID33030429
PMCPMC7544505
OpenAlexW3092319528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.