Evidence map›Paper›PMID 33029812›Full record

Trial reportSeminars in dialysis2021

The calcium concentration of peritoneal dialysis solution modifies levels of key mediators of peritoneal fibrosis.

Chusheng Miao, Xiangliang Xue, Li Dai, Ruiyu Zhao, Zhangjian Zhao, Hanlei Song, Huanlin Jin, Shanshan Li, Zengqi Xue

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Seminars in dialysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Chusheng MiaoDepartment of Nephrology, Rui'an People's Hospital, Rui'an City, Zhejiang Province, China.
Xiangliang XueBiology and Premed, Gordon College, Wenham, MA, USA.
Li DaiDepartment of Nephrology, Rui'an People's Hospital, Rui'an City, Zhejiang Province, China.
Ruiyu ZhaoDepartment of Nephrology, Rui'an People's Hospital, Rui'an City, Zhejiang Province, China.
Zhangjian ZhaoDepartment of Nephrology, Rui'an People's Hospital, Rui'an City, Zhejiang Province, China.
Hanlei SongDepartment of Nephrology, Rui'an People's Hospital, Rui'an City, Zhejiang Province, China.
Huanlin JinDepartment of Nephrology, Rui'an People's Hospital, Rui'an City, Zhejiang Province, China.
Shanshan LiDepartment of Nephrology, Rui'an People's Hospital, Rui'an City, Zhejiang Province, China.
Zengqi XueDepartment of Nephrology, Rui'an People's Hospital, Rui'an City, Zhejiang Province, China.ORCID 0000-0003-0770-0803
Wenzhou Medical University · CNGordon College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo explore the effects of different calcium concentrations of peritoneal dialysis solution (PDS) on continuous ambulatory peritoneal dialysis (CAPD) and expression of vimentin (VIM), fibroblast-specific protein (FSP1), and E-cadherin. MATERIALS AND

methodsThis was a pilot study (#ChiCTR1900021387) conducted from January 2017 to December 2019 at the Hospital. The patients were randomized to undergo CAPD using PDS with a calcium concentration of 1.25 mmol/L (low concentration group) or 1.75 mmol/L (high concentration group). Changes in biochemistry before dialysis and at 6 and 12 months were analyzed.

resultsThere were 50 and 52 participants in the low and high calcium groups. The blood biochemical indexes were all different between the two groups (all P

conclusionThe calcium concentration in PDS might be an important factor affecting the progression of peritoneal fibrosis.

Indexed as

Peritoneal DialysisPeritoneal FibrosisCalciumDialysis SolutionsHumansPilot ProjectsRenal DialysisCalciumDialysis Solutionscontinuous ambulatory peritoneal dialysisE-cadherinfibroblast-specific proteinperitoneal fibrosisvimentin

Identifiers

PMID33029812
PMCPMC7891347
OpenAlexW3091894798

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.