Evidence map›Paper›PMID 33029766›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2021

Prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium and Trichomonas vaginalis including relevant resistance-associated mutations in a single center in the Netherlands.

R H T Nijhuis, R G Duinsbergen, A Pol, P C R Godschalk

Abstract read
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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trends in prevalence ofSexually transmitted infections · 2026
    Article
  4. Limited Role ofObstetrics and gynecology international · 2026
    Article
  5. Article
  6. Review
  7. Prevalence ofHealthcare (Basel, Switzerland) · 2023
    Article
  8. The prevalence of Mycoplasma genitalium (MG) and Trichomonas vaginalis (TV) at testing centers in Belgium, Germany, Spain, and the UK using the cobas TV/MG molecular assay.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
  9. Increases in the Macrolide Resistance ofAntibiotics (Basel, Switzerland) · 2022
    Article
  10. Review
  11. Review
  12. Current and Future Trends in the Laboratory Diagnosis of Sexually Transmitted Infections.International journal of environmental research and public health · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

R H T NijhuisDepartment of Medical Microbiology and Medical Immunology, Meander MC, Amersfoort, The Netherlands. rht.nijhuis@meandermc.nl.ORCID https://orcid.org/0000-0003-4203-3858
R G DuinsbergenDepartment of Medical Microbiology and Medical Immunology, Meander MC, Amersfoort, The Netherlands.
A PolNYtor B.V., Nijmegen, The Netherlands.
P C R GodschalkDepartment of Medical Microbiology and Medical Immunology, Meander MC, Amersfoort, The Netherlands.
Meander Medisch Centrum · NL

Funding

European funding for regional development PROJ-00832
6 · The paper itself

Abstract

purposeIn this study, we report the prevalence of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Mycoplasma genitalium (MG) and Trichomonas vaginalis (TV) amongst clinical specimens of patients suspected for sexually transmitted infections received at our laboratory and in addition report the prevalence of resistance-associated mutations (RAM) for ciprofloxacin in NG and azithromycin and moxifloxacin in MG.

methodsAll specimens received from December 2018 to May 2019 were tested for the four pathogens. In addition, the presence of RAM associated with resistance to ciprofloxacin in NG and to azithromycin and moxifloxacin in MG was determined by different real-time PCR assays on all NG- and MG-positive specimens.

resultsCT was detected most often (267/2613, 10.2%), followed by MG (106/2592, 4.1%), NG (41/2613, 1.6%) and TV (10/2592, 0.4%) amongst all specimens. The prevalence of ciprofloxacin RAM in NG was 21.2%, and the prevalence of RAM in MG was 40.6% for azithromycin and 8.1% for moxifloxacin. Nearly all specimens containing moxifloxacin-resistant MG also contained azithromycin-resistant MG.

conclusionCT is found most often in our population followed by MG and NG. By using molecular assays to detect RAM supplementary to pathogen identification of NG and MG, optimal therapy can be advised.

Indexed as

AdolescentAdultAgedAnti-Bacterial AgentsChildChlamydia trachomatisDrug Resistance, BacterialFemaleHumansMaleMiddle AgedMutationMycoplasma genitaliumNeisseria gonorrhoeaeNetherlandsPrevalenceAnti-Bacterial AgentsAntimicrobial resistanceFluoroquinoloneMacrolide

Identifiers

PMID33029766
OpenAlexW3092572382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.