Evidence map›Paper›PMID 33029741›Full record

ArticleMolecular neurobiology2021

Regulation of GSK3β by Ser

Belen Calvo, Tina M Thornton, Mercedes Rincon, Pedro Tranque, Miriam Fernandez

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. GSK3 as a Master Regulator of Cellular Processes.International journal of molecular sciences · 2023
    Article
  3. GSK3β Inhibition by Phosphorylation at SerInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Belen CalvoResearch Institute for Neurological Disabilities (IDINE), Medical School, University of Castilla-La Mancha, 02006, Albacete, Spain.
Tina M ThorntonDepartment of Medicine, Immunobiology Division, University of Vermont, Burlington, VT, 05405, USA.
Mercedes RinconDepartment of Medicine, Immunobiology Division, University of Vermont, Burlington, VT, 05405, USA.
Pedro TranqueResearch Institute for Neurological Disabilities (IDINE), Medical School, University of Castilla-La Mancha, 02006, Albacete, Spain.
Miriam FernandezResearch Institute for Neurological Disabilities (IDINE), Medical School, University of Castilla-La Mancha, 02006, Albacete, Spain. Miriam.Fernandez@uclm.es.ORCID https://orcid.org/0000-0001-8261-9875
University of Castilla-La Mancha · ESUniversity of Vermont · US

Funding

P53 and cell cycle checkpoint by p38 MAP kinaseR01AI051454 · NIAID · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI RINCON, MERCEDES · 2003 to 2019
$4.9M
GSK3b and dsRNA in CD8 cellsR21AI167201 · NIAID · UNIVERSITY OF COLORADO DENVER · PI RINCON, MERCEDES · 2022 to 2023
$428k
IL-6 and IL-6R genetic polymorphisms in immune-related adverse events caused by cancer immunotherapyR21CA287678 · NCI · UNIVERSITY OF COLORADO DENVER · PI RINCON, MERCEDES · 2024 to 2024
$401k
Ministerio de Economía y Competitividad BFU2015-66926-PNCI NIH HHS R21 CA287678NIAID NIH HHS R01 AI051454NIAID NIH HHS R21 AI167201
6 · The paper itself

Abstract

GSK3β is a constitutively active kinase that promotes cell death, which requires strict regulatory mechanisms. Although Akt-mediated phosphorylation at Ser

Indexed as

AgingAnimalsAnimals, NewbornAstrocytesBrainCell NucleusCells, CulturedDNA DamageGlycogen Synthase Kinase 3 betaMiceMice, Inbred C57BLMicrogliaNeural Stem CellsNeuronsPhosphorylationPhosphoserineGlycogen Synthase Kinase 3 betaPhosphoserineAstrocytesDNA double-strand breaks (DSBs)MicrogliaNeural precursor cells (NPCs)Neuronsp38 MAPK

Identifiers

PMID33029741
OpenAlexW3092090387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.