ArticleSurgical endoscopy2021
Impact of periampullary diverticulum on biliary cannulation and ERCP outcomes: a single-center experience.
Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03771547 (ERCP in Super-aged Patients Considering Difficult Cannulation), which is not on this map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ERCP in Super-aged Patients Considering Difficult Cannulation: Challenges and Adverse Events
Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Endoscopic sphincterotomy with balloon dilation vs. monotherapy for choledocholithiasis in periampullary diverticulum: a randomized trial.Scientific reports · 2025Trial
- Impact of Periampullary Diverticulum on ERCP Outcomes and Recurrence of Common Bile Duct Stones.Digestive diseases and sciences · 2026Article
- Impact of Papillary Morphology and Diverticular Type on Needle-Knife Papillotomy in Patients with Periampullary Diverticulum with Difficult Biliary Cannulation.Journal of clinical medicine · 2025Article
- Impact of periampullary diverticulum on the incidence of post-endoscopic retrograde cholangiography pancreatitis.World journal of gastrointestinal endoscopy · 2025Article
- Impact of periampullary diverticulum and relevant cannulation techniques on the outcomes of endoscopic retrograde cholangiopancreatography: a retrospective study.BMC gastroenterology · 2025Article
- A Challenging Case of Endoscopic Retrograde Cholangiopancreatography Due to an Intradiverticular Papilla.Cureus · 2025Article
- Development of a Scoring System for Predicting the Difficulty of Bile Duct Cannulation and Selecting the Appropriate Cannulation Method.Digestive diseases and sciences · 2025Article
- Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation.World journal of gastroenterology · 2025Observational
- Efficacy and Safety of Endoscopic Retrograde Cholangiopancreatography for the Longevous Population.Clinical interventions in aging · 2025Article
- Optimal timing for discontinuation of ERCP in cases of difficult selective biliary cannulation.Endoscopy international open · 2025Article
- Comparison of ERCP Outcomes and Complication Risk between Elderly and Younger Patients: A Large Single-Center Study.Journal of clinical medicine · 2024Article
- Periampullary submucosal saline injection to facilitate intradiverticular papillary biliary cannulation.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2024Article
- The impact of periampullary diverticula on cannulation and adverse events in endoscopic retrograde cholangiopancreatography.Therapeutic advances in gastroenterology · 2024Article
- Impact of periampullary diverticulum on endoscopic retrograde cholangiopancreatography: bridging the gap between fiction and reality.Przeglad gastroenterologiczny · 2024Article
- A new classification of periampullary diverticulum: cannulation of papilla on the inner margins of the diverticulum (Type IIa) is more challenging.BMC gastroenterology · 2023Article
- [Acute cholangitis secondary to periampullary duodenal diverticulum. Case report].Revista medica del Instituto Mexicano del Seguro Social · 2023Article
- Predictive factors of needle-knife pre-cut papillotomy failure in patients with difficult biliary cannulation.Scientific reports · 2022Article
- Propensity score-matched analysis for comparing transpancreatic sphincterotomy and needle-knife precut in difficult biliary cannulation.Scientific reports · 2021Article
- Periampullary diverticulum in endoscopic retrograde cholangiopancreatography: A paper tiger?Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
- Factors and techniques associated with endoscopic retrograde cholangiopancreatography outcomes in patients with periampullary diverticulum: Results from a large tertiary center.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriampullary diverticulum (PAD) is frequently come upon during endoscopic retrograde cholangiopancreatography (ERCP), especially in elderly patients. However, less is known about the role of PAD in biliary cannulation difficulty.
aimThis study aims to investigate the association of PAD and difficult cannulation and evaluate the impact of different types of PAD on the cannulation success rate and adverse events.
methodsProspectively collected data on a total of 636 patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) were divided into two groups based on the presence or absence of PAD. Besides, the patients were classified based on the PAD types into three groups. The primary outcomes were cannulation success rate, cannulation time, and ERCP-related adverse events. Further, the difficult cannulation and presence of PAD were analyzed using logistic regression models.
resultsSignificant higher rates of biliary stones, cholangitis, and biliary pancreatitis were observed in the PAD group. Successful selective cannulation was achieved in 97.6% in the PAD group and 95.3% in the control group. The cannulation time was significantly longer in the presence of PAD. There was no significant difference in the rate of overall adverse events and post-ERCP pancreatic PEP. Multivariate analysis showed that type 1 PAD, biliary stones, and cholangitis were factors related to difficult cannulation.
conclusionThe presence of PAD did not affect the duration or success of the ERCP procedure. However, it was associated with longer cannulation time and an increase in the cannulation difficulty, especially with PAD type 1. Clinical Trial Study Registration This study is approved by Nanjing Medical University and registered at ClinicalTrial.gov PRS with ID/NCT03771547/.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.